Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 4659010..4659757 | Replicon | chromosome |
Accession | NZ_CP011339 | ||
Organism | Microcystis panniformis FACHB-1757 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | I4HG17 |
Locus tag | VL20_RS22120 | Protein ID | WP_002791882.1 |
Coordinates | 4659010..4659408 (+) | Length | 133 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | - |
Locus tag | VL20_RS22125 | Protein ID | WP_284525888.1 |
Coordinates | 4659401..4659757 (+) | Length | 119 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
VL20_RS22095 (VL20_5350) | 4654276..4655139 | - | 864 | WP_052277817.1 | WYL domain-containing protein | - |
VL20_RS22100 (VL20_5351) | 4655239..4657404 | + | 2166 | WP_052277818.1 | type I-D CRISPR-associated helicase Cas3' | - |
VL20_RS22105 (VL20_5352) | 4657451..4657693 | + | 243 | WP_052277819.1 | hypothetical protein | - |
VL20_RS22110 (VL20_5353) | 4658039..4658386 | + | 348 | WP_002742891.1 | hypothetical protein | - |
VL20_RS22115 (VL20_5354) | 4658549..4658968 | + | 420 | WP_002742890.1 | nucleotidyltransferase domain-containing protein | - |
VL20_RS22120 (VL20_5355) | 4659010..4659408 | + | 399 | WP_002791882.1 | DUF86 domain-containing protein | Toxin |
VL20_RS22125 (VL20_5356) | 4659401..4659757 | + | 357 | WP_284525888.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
VL20_RS33180 (VL20_5357) | 4659944..4660087 | + | 144 | WP_002742887.1 | hypothetical protein | - |
VL20_RS22130 (VL20_5358) | 4660080..4663523 | + | 3444 | WP_052277820.1 | type I-D CRISPR-associated protein Cas10d/Csc3 | - |
VL20_RS22135 (VL20_5359) | 4663541..4664542 | + | 1002 | WP_052277821.1 | type I-D CRISPR-associated protein Cas7/Csc2 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 4653008..4654204 | 1196 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 15326.56 Da Isoelectric Point: 4.6345
>T54047 WP_002791882.1 NZ_CP011339:4659010-4659408 [Microcystis panniformis FACHB-1757]
MNQYLAELSEYGSITLEDYRTLRERQLAIERLIQLIVQTGIDINYQILKCLDIESPNNARDALFQIVELGILEEHLAVQL
AESIKLRNLLVHLYKKIDPDIVHSSIANILRDYPRYQRSIVQYLDSLEAENG
MNQYLAELSEYGSITLEDYRTLRERQLAIERLIQLIVQTGIDINYQILKCLDIESPNNARDALFQIVELGILEEHLAVQL
AESIKLRNLLVHLYKKIDPDIVHSSIANILRDYPRYQRSIVQYLDSLEAENG
Download Length: 399 bp
>T54047 NZ_CP011339:4659010-4659408 [Microcystis panniformis FACHB-1757]
ATGAATCAATACCTCGCCGAACTTAGCGAGTACGGTTCGATCACCTTAGAGGATTATCGTACATTAAGAGAACGTCAATT
AGCCATAGAAAGGTTAATTCAGCTTATCGTTCAAACTGGCATCGATATCAATTACCAGATTTTAAAATGTTTAGATATCG
AGTCTCCGAATAATGCTCGCGACGCATTATTTCAAATCGTAGAACTGGGAATCTTAGAAGAACACCTAGCCGTTCAACTG
GCCGAGTCTATTAAATTAAGAAACTTACTCGTACACTTATACAAGAAAATTGATCCCGATATTGTTCATTCCTCGATCGC
TAATATTTTACGAGATTATCCTCGCTACCAACGCTCGATCGTTCAATATCTAGATTCCTTGGAGGCAGAAAATGGTTAA
ATGAATCAATACCTCGCCGAACTTAGCGAGTACGGTTCGATCACCTTAGAGGATTATCGTACATTAAGAGAACGTCAATT
AGCCATAGAAAGGTTAATTCAGCTTATCGTTCAAACTGGCATCGATATCAATTACCAGATTTTAAAATGTTTAGATATCG
AGTCTCCGAATAATGCTCGCGACGCATTATTTCAAATCGTAGAACTGGGAATCTTAGAAGAACACCTAGCCGTTCAACTG
GCCGAGTCTATTAAATTAAGAAACTTACTCGTACACTTATACAAGAAAATTGATCCCGATATTGTTCATTCCTCGATCGC
TAATATTTTACGAGATTATCCTCGCTACCAACGCTCGATCGTTCAATATCTAGATTCCTTGGAGGCAGAAAATGGTTAA
Antitoxin
Download Length: 119 a.a. Molecular weight: 13895.05 Da Isoelectric Point: 7.1665
>AT54047 WP_284525888.1 NZ_CP011339:4659401-4659757 [Microcystis panniformis FACHB-1757]
MVKNTKELKIINTINRITTTVEKIPNLKLLILFGSRARREHKPDSDWDLAISYDEANRQTHIKEISNDYLTSLSILSELF
EINRDLIDLIELDRCSPLMKYQVARDGKLIYEKIRETF
MVKNTKELKIINTINRITTTVEKIPNLKLLILFGSRARREHKPDSDWDLAISYDEANRQTHIKEISNDYLTSLSILSELF
EINRDLIDLIELDRCSPLMKYQVARDGKLIYEKIRETF
Download Length: 357 bp
>AT54047 NZ_CP011339:4659401-4659757 [Microcystis panniformis FACHB-1757]
ATGGTTAAAAATACGAAAGAATTGAAAATTATCAATACAATCAATAGAATAACCACGACTGTGGAAAAAATACCGAATTT
AAAACTATTAATTCTCTTCGGTTCTAGAGCGCGCAGAGAGCATAAACCTGATAGCGATTGGGATTTGGCAATTTCATACG
ATGAAGCAAACAGACAAACACATATTAAGGAAATCAGTAATGATTACTTAACTTCTCTCTCTATCTTGAGTGAATTGTTT
GAGATAAACCGTGATTTGATCGATCTAATTGAACTCGATCGCTGTTCTCCATTAATGAAGTATCAAGTCGCACGAGATGG
AAAACTTATCTATGAAAAAATACGGGAGACTTTTTAA
ATGGTTAAAAATACGAAAGAATTGAAAATTATCAATACAATCAATAGAATAACCACGACTGTGGAAAAAATACCGAATTT
AAAACTATTAATTCTCTTCGGTTCTAGAGCGCGCAGAGAGCATAAACCTGATAGCGATTGGGATTTGGCAATTTCATACG
ATGAAGCAAACAGACAAACACATATTAAGGAAATCAGTAATGATTACTTAACTTCTCTCTCTATCTTGAGTGAATTGTTT
GAGATAAACCGTGATTTGATCGATCTAATTGAACTCGATCGCTGTTCTCCATTAATGAAGTATCAAGTCGCACGAGATGG
AAAACTTATCTATGAAAAAATACGGGAGACTTTTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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