Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1533152..1533423 Replicon chromosome
Accession NZ_CP011331
Organism Escherichia coli O104:H4 str. C227-11 isolate 368 shch

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1533282..1533385 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1533152..1533423 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAF13_RS07655 1529707..1530369 - 663 WP_000944256.1 exodeoxyribonuclease X -
AAF13_RS07660 1530393..1531049 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
AAF13_RS07665 1531151..1531381 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AAF13_RS07670 1531520..1531894 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AAF13_RS07675 1531898..1532770 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
AAF13_RS07680 1532783..1533124 + 342 WP_000976472.1 YebY family protein -
- 1533152..1533423 - 272 - - Antitoxin
- 1533282..1533385 + 104 - - Toxin
AAF13_RS07690 1533520..1534176 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
AAF13_RS07695 1534177..1534368 - 192 WP_001296140.1 YebW family protein -
AAF13_RS07700 1534473..1534709 - 237 WP_001295499.1 DUF1480 family protein -
AAF13_RS07705 1534827..1536266 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T54011 NZ_CP011331:1533282-1533385 [Escherichia coli O104:H4 str. C227-11]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT54011 NZ_CP011331:c1533423-1533152 [Escherichia coli O104:H4 str. C227-11]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References