Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4135554..4136110 Replicon chromosome
Accession NZ_CP011303
Organism Serratia liquefaciens strain HUMV-21

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag XJ20_RS19365 Protein ID WP_046374442.1
Coordinates 4135820..4136110 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag XJ20_RS19360 Protein ID WP_046374441.1
Coordinates 4135554..4135832 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XJ20_RS19335 4130889..4131728 - 840 WP_046374438.1 MurR/RpiR family transcriptional regulator -
XJ20_RS19340 4131875..4133461 + 1587 WP_020825345.1 gamma-glutamyltransferase -
XJ20_RS19345 4133489..4133680 + 192 WP_046374439.1 oxalurate catabolism protein HpxX -
XJ20_RS19350 4133677..4135077 + 1401 WP_046374440.1 AtzE family amidohydrolase -
XJ20_RS19355 4135081..4135464 + 384 WP_041415223.1 oxalurate catabolism protein HpxZ -
XJ20_RS19360 4135554..4135832 + 279 WP_046374441.1 ribbon-helix-helix protein, CopG family Antitoxin
XJ20_RS19365 4135820..4136110 + 291 WP_046374442.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XJ20_RS19370 4136120..4137004 - 885 WP_046374443.1 siderophore-interacting protein -
XJ20_RS19375 4137010..4138233 - 1224 WP_046374444.1 MFS transporter -
XJ20_RS19380 4138371..4140116 + 1746 WP_046374445.1 aerobactin synthase IucA -
XJ20_RS19385 4140113..4141063 + 951 WP_046374446.1 acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10684.14 Da        Isoelectric Point: 6.8772

>T53803 WP_046374442.1 NZ_CP011303:4135820-4136110 [Serratia liquefaciens]
VPQLIWTPAALLDIQRLYQFLAAKDRQAAQKTVASIRSSVNILAHHPQAGRPIEDMAIEFREWPIDFGNSGYIALYHFDG
STAVLLAVRHQSEAGN

Download         Length: 291 bp

>T53803 NZ_CP011303:4135820-4136110 [Serratia liquefaciens]
GTGCCACAACTGATATGGACGCCTGCCGCACTGCTCGATATTCAGCGACTGTACCAATTTCTGGCAGCCAAAGATCGCCA
GGCTGCGCAAAAGACCGTGGCATCCATTCGTAGCAGCGTCAATATCCTGGCCCATCATCCTCAGGCCGGTCGGCCCATTG
AAGATATGGCAATTGAATTTAGGGAATGGCCGATCGATTTCGGCAACAGCGGCTATATTGCCCTGTATCATTTTGATGGC
AGCACCGCTGTACTGCTGGCAGTGCGCCATCAAAGTGAAGCCGGTAACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10880.08 Da        Isoelectric Point: 5.2317

>AT53803 WP_046374441.1 NZ_CP011303:4135554-4135832 [Serratia liquefaciens]
MTTAASIKIDDELKQRVQQIAATRQRSAHWIMREAIREYVEREEKREALRKDALQAWETYQTNGKRLTQDEADHWLANLE
KGDDTEIPECHN

Download         Length: 279 bp

>AT53803 NZ_CP011303:4135554-4135832 [Serratia liquefaciens]
ATGACTACGGCTGCATCGATAAAAATTGATGATGAGCTCAAGCAACGGGTGCAACAAATCGCGGCCACGCGTCAGCGAAG
TGCGCACTGGATTATGCGCGAGGCTATCCGTGAATACGTCGAGCGAGAAGAAAAGCGCGAAGCGCTGCGCAAAGACGCAC
TGCAAGCCTGGGAAACGTATCAGACCAATGGTAAACGTCTGACCCAAGACGAGGCTGACCATTGGCTCGCTAATCTGGAA
AAAGGTGATGATACGGAGATACCGGAGTGCCACAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References