Detailed information of TA system TA053786

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/RHH-MazF
• Location: 182888..183406
• Replicon: plasmid pRLLBG43
• Accession: NZ_CP011297
• Organism: Rhodococcus erythropolis strain BG43

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: XU06_RS31365
• Protein ID: WP_046380381.1
• Coordinates: 183104..183406 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: -
• Locus tag: XU06_RS31360
• Protein ID: WP_046380454.1
• Coordinates: 182888..183103 (+)
• Length: 72 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XU06_RS31335	178385..179623	+	1239	WP_046380376.1	hypothetical protein	-
XU06_RS31340	179620..179814	+	195	WP_155404359.1	hypothetical protein	-
XU06_RS31345	179811..180998	+	1188	WP_046380378.1	hypothetical protein	-
XU06_RS31350	181069..182367	+	1299	WP_046380379.1	AAA family ATPase	-
XU06_RS33300	182397..182745	+	349	Protein_194	hypothetical protein	-
XU06_RS31360	182888..183103	+	216	WP_046380454.1	hypothetical protein	Antitoxin
XU06_RS31365	183104..183406	+	303	WP_046380381.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
XU06_RS31370	183435..185387	+	1953	WP_046380382.1	hypothetical protein	-
XU06_RS31375	185387..186184	+	798	WP_046380383.1	hypothetical protein	-
XU06_RS31380	186315..187364	-	1050	WP_052741076.1	DUF1016 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..261537	261537

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 12963.60 Da
• Isoelectric Point: 12.8000

>T53786 WP_046380381.1 NZ_CP011297:183104-183406 [Rhodococcus erythropolis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 303 bp

>T53786 NZ_CP011297:183104-183406 [Rhodococcus erythropolis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 72 a.a.
• Molecular weight: 9246.55 Da
• Isoelectric Point: 12.6512

>AT53786 WP_046380454.1 NZ_CP011297:182888-183103 [Rhodococcus erythropolis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 216 bp

>AT53786 NZ_CP011297:182888-183103 [Rhodococcus erythropolis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA