Detailed information of TA system TA053784

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): TsxAB/Xre(antitoxin)
• Location: 18409..18910
• Replicon: plasmid unnamed2
• Accession: NZ_CP011294
• Organism: Salmonella enterica subsp. diarizonae strain 11-01854

Toxin (Protein)

• Gene name: TsxA
• Uniprot ID: A0A6X6XTU7
• Locus tag: UQ49_RS22745
• Protein ID: WP_000702245.1
• Coordinates: 18650..18910 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: TsxB
• Uniprot ID: -
• Locus tag: UQ49_RS22740
• Protein ID: WP_052989132.1
• Coordinates: 18409..18660 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
UQ49_RS22695	13699..14406	+	708	WP_063390999.1	hypothetical protein	-
UQ49_RS22700	14507..14866	+	360	WP_024147837.1	hypothetical protein	-
UQ49_RS22705	14868..15194	+	327	WP_000206697.1	hypothetical protein	-
UQ49_RS22710	15454..15753	-	300	WP_000466320.1	type II toxin-antitoxin system HicB family antitoxin	-
UQ49_RS22715	16255..16437	+	183	WP_001428470.1	hypothetical protein	-
UQ49_RS22720	16525..16872	-	348	WP_000681609.1	type II toxin-antitoxin system HicB family antitoxin	-
UQ49_RS22725	16869..17117	-	249	WP_000513532.1	type II toxin-antitoxin system HicA family toxin	-
UQ49_RS22730	17582..17860	-	279	WP_000545937.1	hypothetical protein	-
UQ49_RS22740	18409..18660	-	252	WP_052989132.1	transcriptional regulator	Antitoxin
UQ49_RS22745	18650..18910	-	261	WP_000702245.1	hypothetical protein	Toxin
UQ49_RS22750	18962..19186	-	225	WP_000814383.1	hypothetical protein	-
UQ49_RS22755	19284..19493	-	210	WP_000866037.1	hypothetical protein	-
UQ49_RS22760	19534..19857	-	324	WP_000427402.1	hypothetical protein	-
UQ49_RS22770	20436..20765	-	330	WP_000855121.1	hypothetical protein	-
UQ49_RS22780	21364..22029	+	666	WP_000532148.1	P-loop NTPase	-
UQ49_RS25395	22103..22387	+	285	WP_001162371.1	hypothetical protein	-
UQ49_RS22790	22405..23001	-	597	WP_000125164.1	hypothetical protein	-
UQ49_RS22795	23151..23312	-	162	WP_001434039.1	type I toxin-antitoxin system Hok family toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..57955	57955

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 12822.38 Da
• Isoelectric Point: 5.5500

>T53784 WP_000702245.1 NZ_CP011294:c18910-18650 [Salmonella enterica subsp. diarizonae]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFF

Nucleotide

• Length: 261 bp

>T53784 NZ_CP011294:c18910-18650 [Salmonella enterica subsp. diarizonae]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 12380.85 Da
• Isoelectric Point: 5.5500

>AT53784 WP_052989132.1 NZ_CP011294:c18660-18409 [Salmonella enterica subsp. diarizonae]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Nucleotide

• Length: 252 bp

>AT53784 NZ_CP011294:c18660-18409 [Salmonella enterica subsp. diarizonae]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTT

Structures

Toxin

• AlphaFold DB: A0A6X6XTU7