Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2613299..2614221 Replicon chromosome
Accession NZ_CP011272
Organism Pirellula sp. SH-Sr6A

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag VN12_RS10300 Protein ID WP_205855244.1
Coordinates 2613299..2613760 (-) Length 154 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag VN12_RS10305 Protein ID WP_146676734.1
Coordinates 2613763..2614221 (-) Length 153 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VN12_RS25785 2608498..2608668 - 171 WP_168164321.1 hypothetical protein -
VN12_RS10275 2608742..2609308 + 567 WP_146676729.1 hypothetical protein -
VN12_RS10280 2609447..2609914 + 468 WP_146676730.1 hypothetical protein -
VN12_RS10285 2610172..2610882 + 711 WP_168164322.1 hypothetical protein -
VN12_RS10290 2611766..2612446 + 681 WP_146676732.1 hypothetical protein -
VN12_RS10295 2612436..2613221 - 786 WP_146676601.1 IS5 family transposase -
VN12_RS10300 2613299..2613760 - 462 WP_205855244.1 PIN domain-containing protein Toxin
VN12_RS10305 2613763..2614221 - 459 WP_146676734.1 helix-turn-helix domain-containing protein Antitoxin
VN12_RS10310 2614514..2618179 + 3666 WP_146676735.1 RHS repeat protein -
VN12_RS10315 2618182..2618697 + 516 WP_146676736.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-113)

Antitoxin

Helix-turn-helix domain, group 17

(82-128)


Sequences

Toxin        


Download         Length: 154 a.a.        Molecular weight: 17259.82 Da        Isoelectric Point: 4.7648

>T53748 WP_205855244.1 NZ_CP011272:c2613760-2613299 [Pirellula sp. SH-Sr6A]
VTQFTVVYDACVLYPAALRDFLMHLAITNLFRARWTDMIHDEWIRNVLKDRPDLEASQLDRTRQLMDAHVFDCLVTGYES
LIPSLSLPDEDDRHVLAAAIRCGADSIVTFNIKDFPKSALEPYGIEALHPDEFVLSHMGLAPNLVCAAAKNVF

Download         Length: 462 bp

>T53748 NZ_CP011272:c2613760-2613299 [Pirellula sp. SH-Sr6A]
GTGACGCAGTTCACCGTCGTCTACGATGCCTGCGTGCTGTACCCGGCAGCGCTTCGCGACTTTCTCATGCATCTAGCGAT
CACGAATCTGTTTCGAGCTCGATGGACCGACATGATTCACGACGAGTGGATTCGCAACGTGCTGAAAGATCGCCCCGACC
TCGAGGCGAGCCAACTTGACCGAACCAGGCAACTCATGGATGCCCACGTGTTCGACTGTTTGGTGACAGGGTATGAATCG
CTGATACCATCTCTGTCGTTGCCTGACGAGGACGATCGGCATGTGTTGGCAGCAGCAATTCGCTGCGGCGCAGATTCCAT
AGTCACCTTCAACATAAAGGATTTTCCCAAGAGCGCCCTCGAACCGTATGGGATAGAAGCACTTCATCCTGACGAGTTCG
TATTGTCACACATGGGCCTTGCGCCGAACCTTGTTTGCGCAGCTGCTAAGAACGTGTTTTGA

Antitoxin


Download         Length: 153 a.a.        Molecular weight: 16860.34 Da        Isoelectric Point: 7.2056

>AT53748 WP_146676734.1 NZ_CP011272:c2614221-2613763 [Pirellula sp. SH-Sr6A]
MISQMQYPPSRDDEELAMASSRSIARIVSSKSDSPLSLRVSTQNGDETVVSVPASAFKLLGDILNEMAKGNAVTLIPVHA
ELTTQQAAELLGVSRPFIVEQLEKGNIPFRKVGTHRRVLFRDLMEYKRSMDRKRLESLDELAAEAQKLGLGY

Download         Length: 459 bp

>AT53748 NZ_CP011272:c2614221-2613763 [Pirellula sp. SH-Sr6A]
ATGATTTCCCAGATGCAGTATCCCCCAAGTCGTGACGACGAAGAACTTGCGATGGCTTCGAGCAGAAGCATTGCCAGAAT
CGTTTCCAGTAAGTCAGACTCGCCACTAAGTTTGCGGGTCAGTACACAAAACGGGGATGAGACGGTGGTGTCCGTACCGG
CATCAGCATTTAAGTTGCTTGGGGACATCCTAAACGAGATGGCGAAAGGCAACGCTGTAACGCTGATCCCTGTGCATGCG
GAGTTAACGACTCAGCAAGCTGCAGAATTGCTGGGCGTATCGCGGCCTTTCATTGTTGAGCAGCTTGAAAAGGGAAACAT
CCCTTTCCGAAAAGTTGGAACGCATCGCCGAGTTTTGTTCAGAGACTTAATGGAATACAAACGGTCGATGGATCGTAAGC
GACTAGAGTCGCTGGATGAATTGGCGGCAGAAGCGCAAAAGCTGGGCTTGGGATACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References