Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 201209..202644 Replicon chromosome
Accession NZ_CP011261
Organism Mycoplasma mycoides subsp. mycoides strain Ben50

Toxin (Protein)


Gene name abiEii Uniprot ID -
Locus tag MmmBen50_RS00890 Protein ID WP_230592171.1
Coordinates 201209..201961 (-) Length 251 a.a.

Antitoxin (Protein)


Gene name abiEi Uniprot ID -
Locus tag MmmBen50_RS00895 Protein ID WP_060954610.1
Coordinates 202048..202644 (-) Length 199 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MmmBen50_RS06910 196391..196816 + 426 WP_011166371.1 transglutaminase domain-containing protein -
MmmBen50_RS06915 196889..197401 + 513 WP_237076078.1 hypothetical protein -
MmmBen50_RS06920 (MmmBen50_0177) 197547..197741 + 195 WP_011166373.1 hypothetical protein -
MmmBen50_RS06465 (MmmBen50_0178) 197810..197974 + 165 WP_015545676.1 hypothetical protein -
MmmBen50_RS00875 (MmmBen50_0181) 198087..199637 + 1551 Protein_171 IS1634-like element IS1634 family transposase -
MmmBen50_RS06525 199754..201168 + 1415 WP_162492251.1 IS3 family transposase -
MmmBen50_RS00890 (MmmBen50_0184) 201209..201961 - 753 WP_230592171.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MmmBen50_RS00895 (MmmBen50_0185) 202048..202644 - 597 WP_060954610.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MmmBen50_RS00900 (MmmBen50_0186) 202854..204158 - 1305 WP_011166379.1 BspA family leucine-rich repeat surface protein -
MmmBen50_RS00905 (MmmBen50_0187) 204264..206954 - 2691 WP_011166380.1 alanine--tRNA ligase -
MmmBen50_RS00910 (MmmBen50_0188) 207026..207520 - 495 WP_011166381.1 membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(4-228)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(6-53)


Sequences

Toxin        


Download         Length: 251 a.a.        Molecular weight: 29576.82 Da        Isoelectric Point: 9.3212

>T53743 WP_230592171.1 NZ_CP011261:c201961-201209 [Mycoplasma mycoides subsp. mycoides]
MISILEKIVKSKNKQNFVIKGGFLLSNMMSLNERTTQDIDCLIKGINFVKENILRTISDVLRYDFTDFIKYEIKEITEIK
KRDKYNGFRVKILCKLEKLEEIVKIDLAIGDVVTPSEIKYNFRNIFSNSSFEIQAYNLETILAEKIFIINNLNIQSTRIK
DLYDIFLIYSFKEFEIDYNILKCACLNTFKKRNTVFNIDLVLSLLNEINQLDIFELLNNYRQKYFYAQKIEFKILIKSVI
KFLEKLKNI

Download         Length: 753 bp

>T53743 NZ_CP011261:c201961-201209 [Mycoplasma mycoides subsp. mycoides]
ATGATATCCATATTAGAAAAAATTGTTAAAAGTAAAAATAAACAAAACTTTGTAATTAAAGGTGGGTTCTTACTTTCTAA
TATGATGAGTTTAAACGAAAGAACCACTCAAGATATAGATTGCTTAATAAAAGGTATCAATTTTGTTAAAGAGAATATTC
TAAGAACTATTTCTGATGTATTAAGATATGATTTTACTGACTTTATAAAATATGAAATAAAAGAAATAACAGAAATAAAA
AAGAGAGACAAATATAATGGATTTAGAGTCAAAATATTATGCAAATTAGAAAAGTTGGAAGAAATAGTAAAAATAGATTT
AGCAATTGGTGATGTTGTAACACCGTCTGAGATTAAATACAATTTTAGAAATATCTTTTCAAATAGTAGCTTTGAAATAC
AAGCATATAATCTAGAAACAATATTAGCTGAAAAAATATTTATAATTAATAATTTAAATATACAATCAACTAGAATAAAA
GATCTTTATGATATTTTTTTAATATATAGCTTTAAAGAGTTTGAGATTGATTATAATATTCTAAAATGTGCTTGTTTAAA
TACTTTTAAAAAAAGAAATACTGTTTTTAATATAGATTTAGTACTTAGTTTATTAAATGAAATTAACCAATTAGATATTT
TTGAATTACTTTGAAATAATTACAGGCAAAAATACTTTTACGCCCAAAAAATAGAATTTAAAATACTGATAAAATCTGTA
ATTAAGTTTTTAGAAAAGTTAAAAAATATTTAA

Antitoxin


Download         Length: 199 a.a.        Molecular weight: 23623.28 Da        Isoelectric Point: 9.3217

>AT53743 WP_060954610.1 NZ_CP011261:c202644-202048 [Mycoplasma mycoides subsp. mycoides]
MNYKEQLIKEAKKRAGIITRKEIMNLKIPSIYITRMIRSNELEKVDIGIYALTSENWYYDPDYNFSIRHKTPIFSYTYAL
TFFDFTDVIPMFRDVTVYHGYNAHNLDPQTRVHYVSKDIYELGVVEVKTNCGNKVRAYDIERTICDFIKHRDKIEAELFA
KTMYKYSEYEKRDKKLHEYAKKMNIGKKVYEVFQVLV

Download         Length: 597 bp

>AT53743 NZ_CP011261:c202644-202048 [Mycoplasma mycoides subsp. mycoides]
ATGAATTATAAAGAACAGCTGATAAAAGAAGCTAAAAAAAGAGCCGGTATTATTACAAGAAAAGAAATTATGAATTTAAA
AATTCCATCAATTTATATTACAAGAATGATTAGAAGTAATGAATTAGAAAAAGTCGATATTGGTATTTATGCTCTAACTT
CTGAAAATTGGTACTATGATCCTGATTATAATTTTAGTATCAGACATAAAACACCTATTTTTTCTTATACTTATGCACTT
ACATTTTTTGATTTTACAGATGTTATTCCAATGTTTCGTGATGTAACTGTTTATCATGGATATAATGCTCATAATTTAGA
CCCACAAACTAGAGTACACTATGTTTCAAAAGATATATATGAACTTGGAGTTGTAGAAGTAAAAACAAATTGTGGTAATA
AAGTTAGAGCTTATGATATTGAAAGAACAATTTGTGATTTTATTAAGCATAGAGATAAAATCGAAGCTGAACTATTTGCA
AAAACTATGTATAAATATTCTGAATATGAAAAAAGAGATTGAAAAAAACTTCATGAATATGCTAAAAAAATGAACATTGG
TAAGAAAGTTTATGAAGTTTTTCAAGTATTAGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References