53738

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 3542949..3543314 Replicon chromosome
Accession NZ_CP011256
Organism Xanthomonas arboricola strain 17

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag XB05_RS14935 Protein ID WP_016904515.1
Coordinates 3542949..3543083 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag XB05_RS14940 Protein ID WP_006451340.1
Coordinates 3543162..3543314 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XB05_RS14920 3540016..3540960 - 945 WP_046344906.1 MBL fold metallo-hydrolase -
XB05_RS14925 3541018..3542307 - 1290 WP_046344908.1 tryptophan--tRNA ligase -
XB05_RS14930 3542489..3542698 - 210 WP_016904514.1 CsbD family protein -
XB05_RS14935 3542949..3543083 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
XB05_RS14940 3543162..3543314 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
XB05_RS14945 3543425..3544348 - 924 WP_046346094.1 arginase -
XB05_RS14950 3544827..3545279 + 453 WP_046344911.1 roadblock/LC7 domain-containing protein -
XB05_RS14955 3545344..3545703 + 360 WP_016904518.1 hypothetical protein -
XB05_RS14960 3545798..3546715 + 918 WP_046344913.1 hypothetical protein -
XB05_RS14965 3546712..3547254 + 543 WP_016904520.1 GTPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T53738 WP_016904515.1 NZ_CP011256:c3543083-3542949 [Xanthomonas arboricola]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T53738 NZ_CP011256:c3543083-3542949 [Xanthomonas arboricola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGGTGTTGTCGGTCGGTATGCTGTCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCTGCGCGCAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT53738 WP_006451340.1 NZ_CP011256:c3543314-3543162 [Xanthomonas arboricola]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT53738 NZ_CP011256:c3543314-3543162 [Xanthomonas arboricola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
CGGCAAGGACATGCAGGGTGCAGGCGAGAAGGTCGAAAAGAAGGCCGACAACTGCAGCGACGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0


Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References