Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5255767..5255869 Replicon chromosome
Accession NZ_CP011254
Organism Serratia fonticola strain DSM 4576

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5255774..5255869 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5255767..5255860 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WN53_RS23275 5251325..5252014 - 690 WP_024485872.1 DUF4145 domain-containing protein -
WN53_RS23280 5252262..5252645 - 384 WP_024485871.1 DUF2570 family protein -
WN53_RS23285 5252642..5253268 - 627 WP_024485870.1 glycoside hydrolase family 19 protein -
WN53_RS26950 5253273..5253683 - 411 WP_052754330.1 phage holin family protein -
WN53_RS28285 5253831..5254274 + 444 WP_024485868.1 hypothetical protein -
WN53_RS23300 5254570..5255238 - 669 WP_024485867.1 hypothetical protein -
WN53_RS27750 5255556..5255723 - 168 WP_167669108.1 DUF1133 family protein -
- 5255767..5255860 + 94 - - Antitoxin
- 5255774..5255869 - 96 - - Toxin
WN53_RS23305 5256010..5256351 - 342 WP_021806756.1 YebY family protein -
WN53_RS23310 5256421..5257302 - 882 WP_024485866.1 copper homeostasis membrane protein CopD -
WN53_RS23315 5257306..5257689 - 384 WP_024485865.1 CopC domain-containing protein YobA -
WN53_RS23320 5258130..5258648 - 519 WP_024485864.1 non-heme ferritin -
WN53_RS23325 5259038..5259268 + 231 WP_024485863.1 DNA polymerase III subunit theta -
WN53_RS23330 5259404..5260393 - 990 WP_046808321.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5228387..5269140 40753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 96 bp

>T53726 NZ_CP011254:c5255869-5255774 [Serratia fonticola]
AACAAACCTTGCATAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCCTTTCCCTAGACCGAGTATAGGAATCG
TACTCGGTCTTTTTTT

Antitoxin


Download         Length: 94 bp

>AT53726 NZ_CP011254:5255767-5255860 [Serratia fonticola]
AAAAGATAAAAAAAGACCGAGTACGATTCCTATACTCGGTCTAGGGAAAGGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTTATGCA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References