Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 163746..164290 Replicon chromosome
Accession NZ_CP011250
Organism Xanthomonas citri pv. aurantifolii strain FDC 1561

Toxin (Protein)


Gene name relE Uniprot ID A0A1U8YMX6
Locus tag TP45_RS00840 Protein ID WP_042675357.1
Coordinates 163746..164045 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Z7EKF2
Locus tag TP45_RS00845 Protein ID WP_029818122.1
Coordinates 164033..164290 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TP45_RS00810 159546..160619 + 1074 WP_042675364.1 hypothetical protein -
TP45_RS00820 160834..161745 - 912 WP_007964858.1 LysR family transcriptional regulator -
TP45_RS00825 161871..162608 + 738 WP_007964860.1 SDR family oxidoreductase -
TP45_RS00830 162668..163567 + 900 WP_007964861.1 SDR family NAD(P)-dependent oxidoreductase -
TP45_RS00840 163746..164045 - 300 WP_042675357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TP45_RS00845 164033..164290 - 258 WP_029818122.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
TP45_RS00850 164356..165018 - 663 WP_029818121.1 hemolysin III family protein -
TP45_RS00855 165196..167691 + 2496 WP_007964866.1 DEAD/DEAH box helicase -
TP45_RS00860 167688..169157 + 1470 WP_088411810.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11247.97 Da        Isoelectric Point: 9.7235

>T53705 WP_042675357.1 NZ_CP011250:c164045-163746 [Xanthomonas citri pv. aurantifolii]
MAEIIWSVPALADLDAIADYTAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T53705 NZ_CP011250:c164045-163746 [Xanthomonas citri pv. aurantifolii]
ATGGCTGAAATAATCTGGTCAGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACACCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACATCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAAATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9632.12 Da        Isoelectric Point: 8.6223

>AT53705 WP_029818122.1 NZ_CP011250:c164290-164033 [Xanthomonas citri pv. aurantifolii]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVADGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT53705 NZ_CP011250:c164290-164033 [Xanthomonas citri pv. aurantifolii]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1U8YMX6

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z7EKF2

References