Detailed information of TA system TA053703

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 121008..121555
• Replicon: plasmid pAt
• Accession: NZ_CP011248
• Organism: Agrobacterium fabacearum strain Ach5

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: Ach5_RS23775
• Protein ID: WP_038496495.1
• Coordinates: 121262..121555 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A7U5CZ68
• Locus tag: Ach5_RS23770
• Protein ID: WP_003519100.1
• Coordinates: 121008..121262 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Ach5_RS23755	116521..118281	+	1761	WP_038496489.1	penicillin-binding protein 2	-
Ach5_RS23760	118275..118895	-	621	WP_075807885.1	TetR/AcrR family transcriptional regulator	-
Ach5_RS26835	119507..120672	-	1166	Protein_121	IS110 family transposase	-
Ach5_RS23770	121008..121262	+	255	WP_003519100.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
Ach5_RS23775	121262..121555	+	294	WP_038496495.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Ach5_RS26840	121977..123346	+	1370	Protein_124	transposase	-
Ach5_RS23785	123700..124599	+	900	WP_046205651.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..544752	544752

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (25-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-68)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 12579.08 Da
• Isoelectric Point: 12.7867

>T53703 WP_038496495.1 NZ_CP011248:121262-121555 [Agrobacterium fabacearum]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 294 bp

>T53703 NZ_CP011248:121262-121555 [Agrobacterium fabacearum]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 10912.81 Da
• Isoelectric Point: 12.7242

>AT53703 WP_003519100.1 NZ_CP011248:121008-121262 [Agrobacterium fabacearum]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKK

Nucleotide

• Length: 255 bp

>AT53703 NZ_CP011248:121008-121262 [Agrobacterium fabacearum]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

Structures

Antitoxin

• AlphaFold DB: A0A7U5CZ68