Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 23249..23786 Replicon plasmid pXfc37
Accession NZ_CP011164
Organism Xanthomonas citri pv. aurantifolii strain FDC 1609

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9YU06
Locus tag TP50_RS23620 Protein ID WP_017158383.1
Coordinates 23505..23786 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7X9UWY6
Locus tag TP50_RS23615 Protein ID WP_017158384.1
Coordinates 23249..23518 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TP50_RS23595 19835..20537 - 703 Protein_21 UPF0149 family protein -
TP50_RS23600 20755..20934 - 180 WP_080582270.1 hypothetical protein -
TP50_RS23605 21333..22019 + 687 WP_007968793.1 DNA-binding protein -
TP50_RS23610 22178..23140 + 963 WP_088409645.1 recombinase family protein -
TP50_RS23615 23249..23518 + 270 WP_017158384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
TP50_RS23620 23505..23786 + 282 WP_017158383.1 type II toxin-antitoxin system YafQ family toxin Toxin
TP50_RS23625 24002..24892 + 891 WP_108702711.1 restriction endonuclease -
TP50_RS23630 24901..25569 - 669 WP_007968835.1 S-adenosylmethionine-binding protein -
TP50_RS24560 25583..25807 - 225 WP_131458977.1 hypothetical protein -
TP50_RS23635 26006..26359 - 354 WP_033481414.1 hypothetical protein -
TP50_RS23640 26405..27112 - 708 WP_088409646.1 plasmid stabilization protein -
TP50_RS23645 27109..27555 - 447 WP_033481413.1 hypothetical protein -
TP50_RS23650 27903..28298 + 396 WP_007966864.1 hypothetical protein -
TP50_RS23655 28298..28486 + 189 WP_017162389.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..37089 37089


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-86)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10679.06 Da        Isoelectric Point: 8.9188

>T53593 WP_017158383.1 NZ_CP011164:23505-23786 [Xanthomonas citri pv. aurantifolii]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Download         Length: 282 bp

>T53593 NZ_CP011164:23505-23786 [Xanthomonas citri pv. aurantifolii]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCCGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT53593 WP_017158384.1 NZ_CP011164:23249-23518 [Xanthomonas citri pv. aurantifolii]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Download         Length: 270 bp

>AT53593 NZ_CP011164:23249-23518 [Xanthomonas citri pv. aurantifolii]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9YU06

Antitoxin

Source ID Structure
AlphaFold DB A0A7X9UWY6

References