53592

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4650624..4650985 Replicon chromosome
Accession NZ_CP011163
Organism Xanthomonas citri pv. aurantifolii strain FDC 1609

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag TP50_RS21175 Protein ID WP_005914328.1
Coordinates 4650624..4650758 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag TP50_RS21180 Protein ID WP_003486606.1
Coordinates 4650833..4650985 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TP50_RS21160 4647653..4648696 - 1044 WP_007974176.1 MBL fold metallo-hydrolase -
TP50_RS21165 4648726..4650015 - 1290 WP_007966942.1 tryptophan--tRNA ligase -
TP50_RS21170 4650188..4650397 - 210 WP_016904514.1 CsbD family protein -
TP50_RS21175 4650624..4650758 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
TP50_RS21180 4650833..4650985 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
TP50_RS21185 4651092..4652015 - 924 WP_007966941.1 arginase -
TP50_RS21190 4652336..4652788 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
TP50_RS21195 4652852..4653211 + 360 WP_003486613.1 hypothetical protein -
TP50_RS21200 4653308..4654225 + 918 WP_007974173.1 hypothetical protein -
TP50_RS21205 4654222..4654764 + 543 WP_003486615.1 GTPase -
TP50_RS21210 4655244..4655927 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T53592 WP_005914328.1 NZ_CP011163:c4650758-4650624 [Xanthomonas citri pv. aurantifolii]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T53592 NZ_CP011163:c4650758-4650624 [Xanthomonas citri pv. aurantifolii]
ATGAAGCGTGCAATTGTGCTGCTGGTGTTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT53592 WP_003486606.1 NZ_CP011163:c4650985-4650833 [Xanthomonas citri pv. aurantifolii]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT53592 NZ_CP011163:c4650985-4650833 [Xanthomonas citri pv. aurantifolii]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References