Detailed information of TA system TA053589

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 15160..15697
• Replicon: plasmid pXfc38
• Accession: NZ_CP011162
• Organism: Xanthomonas citri pv. aurantifolii strain FDC 1559

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A0P6VGP0
• Locus tag: TP37_RS24055
• Protein ID: WP_042806120.1
• Coordinates: 15416..15697 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7X9UWY6
• Locus tag: TP37_RS24050
• Protein ID: WP_017158384.1
• Coordinates: 15160..15429 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TP37_RS24895	10314..10693	-	380	Protein_14	hypothetical protein	-
TP37_RS24015	11007..11315	-	309	WP_157883188.1	type II toxin-antitoxin system PemK/MazF family toxin	-
TP37_RS24020	11332..11547	-	216	WP_011345582.1	antitoxin MazE family protein	-
TP37_RS24025	11795..12127	-	333	Protein_17	hypothetical protein	-
TP37_RS24030	12124..12755	-	632	Protein_18	ParA family protein	-
TP37_RS24040	13231..13917	+	687	WP_007974125.1	DNA-binding protein	-
TP37_RS24045	14077..15051	+	975	WP_007974204.1	recombinase family protein	-
TP37_RS24050	15160..15429	+	270	WP_017158384.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
TP37_RS24055	15416..15697	+	282	WP_042806120.1	type II toxin-antitoxin system YafQ family toxin	Toxin
TP37_RS24900	17051..17179	-	129	Protein_24	plasmid stabilization protein	-
TP37_RS24070	17176..17631	-	456	WP_088370905.1	conjugal transfer protein TraD	-
TP37_RS24075	18020..18415	+	396	WP_088370906.1	conjugal transfer protein TraA	-
TP37_RS24080	18513..18782	+	270	WP_017158796.1	hypothetical protein	-
TP37_RS24085	18779..19072	+	294	WP_017158795.1	type II toxin-antitoxin system RelE/ParE family toxin	-
TP37_RS24090	19185..19805	+	621	WP_007974812.1	hypothetical protein	-
TP37_RS24095	20005..20347	+	343	Protein_30	hypothetical protein	-
TP37_RS24100	20419..20616	+	198	WP_017158766.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..37980	37980

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-86)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10695.10 Da
• Isoelectric Point: 8.9188

>T53589 WP_042806120.1 NZ_CP011162:15416-15697 [Xanthomonas citri pv. aurantifolii]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPLDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Nucleotide

• Length: 282 bp

>T53589 NZ_CP011162:15416-15697 [Xanthomonas citri pv. aurantifolii]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCTCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCGCGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9719.10 Da
• Isoelectric Point: 5.6976

>AT53589 WP_017158384.1 NZ_CP011162:15160-15429 [Xanthomonas citri pv. aurantifolii]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Nucleotide

• Length: 270 bp

>AT53589 NZ_CP011162:15160-15429 [Xanthomonas citri pv. aurantifolii]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCCAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCCAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Structures

Toxin

• AlphaFold DB: A0A0P6VGP0

Antitoxin

• AlphaFold DB: A0A7X9UWY6