53587

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4680323..4680684 Replicon chromosome
Accession NZ_CP011160
Organism Xanthomonas citri pv. aurantifolii strain FDC 1559

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag TP37_RS21415 Protein ID WP_005914328.1
Coordinates 4680323..4680457 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag TP37_RS21420 Protein ID WP_003486606.1
Coordinates 4680532..4680684 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TP37_RS21400 4677352..4678395 - 1044 WP_007974176.1 MBL fold metallo-hydrolase -
TP37_RS21405 4678425..4679714 - 1290 WP_007966942.1 tryptophan--tRNA ligase -
TP37_RS21410 4679887..4680096 - 210 WP_016904514.1 CsbD family protein -
TP37_RS21415 4680323..4680457 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
TP37_RS21420 4680532..4680684 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
TP37_RS21425 4680791..4681714 - 924 WP_007966941.1 arginase -
TP37_RS21430 4682035..4682487 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
TP37_RS21435 4682551..4682910 + 360 WP_007974174.1 hypothetical protein -
TP37_RS21440 4683007..4683924 + 918 WP_007974173.1 hypothetical protein -
TP37_RS21445 4683921..4684463 + 543 WP_003486615.1 GTPase -
TP37_RS21450 4684943..4685626 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T53587 WP_005914328.1 NZ_CP011160:c4680457-4680323 [Xanthomonas citri pv. aurantifolii]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T53587 NZ_CP011160:c4680457-4680323 [Xanthomonas citri pv. aurantifolii]
ATGAAGCGTGCAATTGTGCTGCTGGTGTTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT53587 WP_003486606.1 NZ_CP011160:c4680684-4680532 [Xanthomonas citri pv. aurantifolii]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT53587 NZ_CP011160:c4680684-4680532 [Xanthomonas citri pv. aurantifolii]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References