Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 72145..72689 Replicon chromosome
Accession NZ_CP011160
Organism Xanthomonas citri pv. aurantifolii strain FDC 1559

Toxin (Protein)


Gene name relE Uniprot ID A0A1U8YMX6
Locus tag TP37_RS00325 Protein ID WP_042675357.1
Coordinates 72390..72689 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Z7EKF2
Locus tag TP37_RS00320 Protein ID WP_029818122.1
Coordinates 72145..72402 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TP37_RS00305 67236..68747 - 1512 WP_007973071.1 ribonuclease H-like domain-containing protein -
TP37_RS00310 68744..71239 - 2496 WP_007973073.1 DEAD/DEAH box helicase -
TP37_RS00315 71417..72079 + 663 WP_029818121.1 hemolysin III family protein -
TP37_RS00320 72145..72402 + 258 WP_029818122.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
TP37_RS00325 72390..72689 + 300 WP_042675357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TP37_RS00335 72869..73768 - 900 WP_007973076.1 SDR family NAD(P)-dependent oxidoreductase -
TP37_RS00340 73827..74564 - 738 WP_007973078.1 SDR family oxidoreductase -
TP37_RS00345 74690..75601 + 912 WP_007973080.1 LysR family transcriptional regulator -
TP37_RS00355 75816..76868 - 1053 WP_007973082.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11247.97 Da        Isoelectric Point: 9.7235

>T53585 WP_042675357.1 NZ_CP011160:72390-72689 [Xanthomonas citri pv. aurantifolii]
MAEIIWSVPALADLDAIADYTAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T53585 NZ_CP011160:72390-72689 [Xanthomonas citri pv. aurantifolii]
ATGGCTGAAATAATCTGGTCAGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACACCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACATCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAAATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9632.12 Da        Isoelectric Point: 8.6223

>AT53585 WP_029818122.1 NZ_CP011160:72145-72402 [Xanthomonas citri pv. aurantifolii]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVADGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT53585 NZ_CP011160:72145-72402 [Xanthomonas citri pv. aurantifolii]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1U8YMX6

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z7EKF2

References