Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 13819..14402 Replicon plasmid unnamed2
Accession NZ_CP011122
Organism Acetobacter oryzifermentans strain SLV-7

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag WG31_RS14135 Protein ID WP_063355046.1
Coordinates 13819..14163 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag WG31_RS14140 Protein ID WP_063355047.1
Coordinates 14160..14402 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WG31_RS14105 9838..10575 + 738 WP_063355040.1 M48 family metallopeptidase -
WG31_RS14110 10755..10943 - 189 WP_063355041.1 hypothetical protein -
WG31_RS15620 11226..11675 - 450 WP_157884545.1 hypothetical protein -
WG31_RS14120 11855..12133 + 279 WP_063355043.1 BrnT family toxin -
WG31_RS14125 12121..12450 + 330 WP_063355044.1 DUF1870 family protein -
WG31_RS14130 12649..13728 - 1080 WP_063355045.1 IS5 family transposase -
WG31_RS14135 13819..14163 - 345 WP_063355046.1 endoribonuclease MazF Toxin
WG31_RS14140 14160..14402 - 243 WP_063355047.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
WG31_RS15715 14619..14876 - 258 WP_063355048.1 hypothetical protein -
WG31_RS14150 15014..16093 + 1080 WP_063355049.1 IS5 family transposase -
WG31_RS14155 16228..16698 - 471 Protein_17 integrase -
WG31_RS14160 17376..18230 + 855 WP_063355050.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..116245 116245


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-113)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12533.73 Da        Isoelectric Point: 9.3043

>T53475 WP_063355046.1 NZ_CP011122:c14163-13819 [Acetobacter oryzifermentans]
VSAKAKTAWVPDCGEIVWLEFDPQAGREQAGHRPAVVLSPACYNVKAGMMLCCPTTTKIKGYPFEVALTGEIASVALSDQ
VRSLDWRVRKAKLKGKVLPEELEAIRQRIRLLVG

Download         Length: 345 bp

>T53475 NZ_CP011122:c14163-13819 [Acetobacter oryzifermentans]
GTGAGTGCCAAAGCAAAGACTGCCTGGGTTCCTGATTGCGGGGAGATTGTCTGGCTGGAATTTGATCCTCAGGCTGGCAG
GGAGCAGGCAGGGCACCGGCCTGCTGTTGTGCTGAGCCCTGCCTGCTATAATGTCAAGGCGGGTATGATGCTGTGCTGCC
CGACAACGACCAAAATCAAAGGCTATCCTTTTGAAGTGGCTCTGACTGGAGAAATTGCCAGTGTAGCCTTGTCAGATCAG
GTGAGAAGTTTGGATTGGCGCGTTAGAAAGGCAAAGCTCAAAGGTAAAGTTTTACCAGAAGAACTTGAGGCCATCCGACA
GCGTATCAGATTGCTGGTCGGGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8727.87 Da        Isoelectric Point: 4.4354

>AT53475 WP_063355047.1 NZ_CP011122:c14402-14160 [Acetobacter oryzifermentans]
MQGVVRKWGNSAAIRLPAGVLDAVSLKIDQAVDVREEDGRIIIEPVRAVPLKLEELVSGITNENRHDEMDFGSSVGGESW

Download         Length: 243 bp

>AT53475 NZ_CP011122:c14402-14160 [Acetobacter oryzifermentans]
ATGCAGGGTGTTGTCAGGAAATGGGGGAACAGTGCAGCCATACGTCTCCCTGCTGGCGTGCTTGACGCCGTCAGTCTGAA
GATTGATCAGGCCGTCGATGTGCGGGAAGAAGATGGACGCATCATCATAGAACCAGTCAGAGCAGTTCCTCTTAAACTGG
AAGAATTAGTTTCCGGTATTACAAACGAGAACCGCCATGATGAAATGGACTTCGGTTCGTCTGTTGGTGGTGAAAGCTGG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References