Detailed information of TA system TA053471

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 93051..93601
• Replicon: plasmid unnamed1
• Accession: NZ_CP011121
• Organism: Acetobacter oryzifermentans strain SLV-7

Toxin (Protein)

• Gene name: relE
• Uniprot ID: C7JII7
• Locus tag: WG31_RS13710
• Protein ID: WP_003618711.1
• Coordinates: 93051..93344 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: D5QDQ9
• Locus tag: WG31_RS13715
• Protein ID: WP_003618686.1
• Coordinates: 93341..93601 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
WG31_RS13680	88535..88900	+	366	WP_010512344.1	DUF488 family protein	-
WG31_RS13685	88962..89351	+	390	WP_003631279.1	PAS domain-containing protein	-
WG31_RS13690	89348..89620	+	273	WP_063354992.1	DUF1971 domain-containing protein	-
WG31_RS13695	89634..89849	-	216	WP_010512346.1	DUF2945 domain-containing protein	-
WG31_RS15205	89885..90463	+	579	WP_006115867.1	DUF488 domain-containing protein	-
WG31_RS15210	90662..91147	+	486	WP_082823248.1	helix-turn-helix domain-containing protein	-
WG31_RS13700	91202..91657	-	456	Protein_97	DUF1275 domain-containing protein	-
WG31_RS13705	91657..92919	-	1263	WP_063355009.1	sodium:proton antiporter	-
WG31_RS13710	93051..93344	-	294	WP_003618711.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
WG31_RS13715	93341..93601	-	261	WP_003618686.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
WG31_RS13725	94190..94993	-	804	WP_012813331.1	type 1 glutamine amidotransferase domain-containing protein	-
WG31_RS13730	95000..95827	-	828	WP_063355011.1	SDR family NAD(P)-dependent oxidoreductase	-
WG31_RS13735	95879..96448	-	570	WP_035366644.1	TetR/AcrR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..165374	165374
	-	flank	IS/Tn	-	-	87721..88146	425

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-86)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-80)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11605.35 Da
• Isoelectric Point: 7.9998

>T53471 WP_003618711.1 NZ_CP011121:c93344-93051 [Acetobacter oryzifermentans]
MKEYCLEFDDRALREWDALDGSVRKKFEKKLEKLIWNPHSPGNELHRDLSGFYKIKLLKDGYRLVYQVIDERIVIYVIAV
GRRADNEIYELASKRTE

Nucleotide

• Length: 294 bp

>T53471 NZ_CP011121:c93344-93051 [Acetobacter oryzifermentans]
ATGAAAGAGTATTGTCTTGAATTCGACGACAGAGCACTCAGAGAGTGGGATGCTCTTGACGGCAGCGTGCGTAAGAAATT
TGAAAAGAAGCTGGAAAAGCTGATCTGGAACCCTCACTCTCCAGGAAACGAACTGCATCGCGACCTATCAGGGTTTTATA
AGATCAAGCTTCTGAAAGATGGTTACCGCCTTGTTTATCAGGTCATCGACGAACGGATCGTCATCTATGTAATTGCCGTT
GGCCGGAGAGCCGATAATGAGATTTATGAACTGGCTTCGAAGCGAACGGAGTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9762.23 Da
• Isoelectric Point: 10.4645

>AT53471 WP_003618686.1 NZ_CP011121:c93601-93341 [Acetobacter oryzifermentans]
MSAVTFRVDETLKAAAVKKLSAQGISLSDALRDTLAYIAETGRSPVKRRLVTDEDAELIEIVRERLKNPAQKHRMTFAEL
KNRHRE

Nucleotide

• Length: 261 bp

>AT53471 NZ_CP011121:c93601-93341 [Acetobacter oryzifermentans]
ATGTCTGCTGTTACATTCCGGGTAGATGAAACGCTGAAGGCAGCCGCAGTTAAGAAGTTGTCGGCTCAAGGCATTTCACT
TTCTGACGCACTGCGCGATACGCTCGCGTATATTGCTGAAACGGGTCGCTCTCCCGTCAAGCGGAGGCTTGTCACAGACG
AGGATGCGGAGCTTATCGAGATTGTGCGCGAACGCCTAAAAAACCCTGCCCAAAAGCATCGTATGACTTTTGCAGAGCTT
AAGAACCGTCATCGCGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A6N3T9M6