Detailed information of TA system TA053470

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 44874..45424
• Replicon: plasmid unnamed1
• Accession: NZ_CP011121
• Organism: Acetobacter oryzifermentans strain SLV-7

Toxin (Protein)

• Gene name: relE
• Uniprot ID: C7JII7
• Locus tag: WG31_RS13480
• Protein ID: WP_003618711.1
• Coordinates: 45131..45424 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: D5QDQ9
• Locus tag: WG31_RS13475
• Protein ID: WP_003618686.1
• Coordinates: 44874..45134 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
WG31_RS13450	41378..42139	-	762	WP_063355005.1	SDR family oxidoreductase	-
WG31_RS13455	42241..43020	+	780	Protein_47	LysR family transcriptional regulator	-
WG31_RS13470	44298..44660	+	363	WP_012813198.1	hypothetical protein	-
WG31_RS13475	44874..45134	+	261	WP_003618686.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
WG31_RS13480	45131..45424	+	294	WP_003618711.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
WG31_RS13485	45610..46143	+	534	WP_006117365.1	hypothetical protein	-
WG31_RS13490	46213..47970	-	1758	WP_006117366.1	oleate hydratase	-
WG31_RS13495	48136..48834	-	699	Protein_54	DUF1275 domain-containing protein	-
WG31_RS13500	49120..49752	+	633	Protein_55	damage-inducible protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..165374	165374

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-86)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-80)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11605.35 Da
• Isoelectric Point: 7.9998

>T53470 WP_003618711.1 NZ_CP011121:45131-45424 [Acetobacter oryzifermentans]
MKEYCLEFDDRALREWDALDGSVRKKFEKKLEKLIWNPHSPGNELHRDLSGFYKIKLLKDGYRLVYQVIDERIVIYVIAV
GRRADNEIYELASKRTE

Nucleotide

• Length: 294 bp

>T53470 NZ_CP011121:45131-45424 [Acetobacter oryzifermentans]
ATGAAAGAGTATTGTCTTGAATTCGACGACAGAGCACTCAGAGAGTGGGATGCTCTTGACGGCAGCGTGCGTAAGAAATT
TGAAAAGAAGCTGGAAAAGCTGATCTGGAACCCTCACTCTCCAGGAAACGAACTGCATCGCGACCTATCAGGGTTTTATA
AGATCAAGCTTCTGAAAGATGGTTACCGCCTTGTTTATCAGGTCATCGACGAACGGATCGTCATCTATGTAATTGCCGTT
GGCCGGAGAGCCGATAATGAGATTTATGAACTGGCTTCGAAGCGAACGGAGTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9762.23 Da
• Isoelectric Point: 10.4645

>AT53470 WP_003618686.1 NZ_CP011121:44874-45134 [Acetobacter oryzifermentans]
MSAVTFRVDETLKAAAVKKLSAQGISLSDALRDTLAYIAETGRSPVKRRLVTDEDAELIEIVRERLKNPAQKHRMTFAEL
KNRHRE

Nucleotide

• Length: 261 bp

>AT53470 NZ_CP011121:44874-45134 [Acetobacter oryzifermentans]
ATGTCTGCTGTTACATTCCGGGTAGATGAAACGCTGAAGGCAGCCGCAGTTAAGAAGTTGTCGGCTCAAGGCATTTCACT
TTCTGACGCACTGCGCGATACGCTCGCGTATATTGCTGAAACGGGTCGCTCTCCCGTCAAGCGGAGGCTTGTCACAGACG
AGGATGCGGAGCTTATCGAGATTGTGCGCGAACGCCTAAAAAACCCTGCCCAAAAGCATCGTATGACTTTTGCAGAGCTT
AAGAACCGTCATCGCGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A6N3T9M6