Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 1282031..1283248 Replicon chromosome
Accession NZ_CP011117
Organism Pseudomonas synxantha strain LBUM223

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag VO64_RS05955 Protein ID WP_046068824.1
Coordinates 1282676..1283248 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag VO64_RS05950 Protein ID WP_046068823.1
Coordinates 1282031..1282588 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VO64_RS05935 1277686..1278408 + 723 WP_046068820.1 molecular chaperone -
VO64_RS05940 1278513..1281023 + 2511 WP_046068821.1 fimbrial biogenesis outer membrane usher protein -
VO64_RS05945 1281083..1281919 + 837 WP_046068822.1 acid phosphatase -
VO64_RS05950 1282031..1282588 + 558 WP_046068823.1 helix-turn-helix domain-containing protein Antitoxin
VO64_RS05955 1282676..1283248 + 573 WP_046068824.1 HD domain-containing protein Toxin
VO64_RS05960 1283258..1283680 - 423 WP_046068825.1 RidA family protein -
VO64_RS05965 1283692..1285275 - 1584 WP_046068826.1 FAD-dependent oxidoreductase -
VO64_RS05970 1285288..1286211 - 924 WP_046068827.1 ABC transporter substrate-binding protein -
VO64_RS05975 1286229..1287002 - 774 WP_046068828.1 amino acid ABC transporter ATP-binding protein -
VO64_RS05980 1286995..1287966 - 972 WP_046068829.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-184)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21287.39 Da        Isoelectric Point: 4.9633

>T53452 WP_046068824.1 NZ_CP011117:1282676-1283248 [Pseudomonas synxantha]
MDLEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERLDLLLLAQSLDSPLKTEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDADPLFEALRALIDRATEQRLHAAE

Download         Length: 573 bp

>T53452 NZ_CP011117:1282676-1283248 [Pseudomonas synxantha]
ATGGACCTGGAAAAAATCAAAGGCCGTCTCGATTTCCTGCGCGAAGCGGAAAAACTCAAGGATGTGCTCAGAAGTGCCCA
CACGGCTTCGGGTCGCACTGAAAGCACGGCCGAACACAGTTGGCGCCTGTGTCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTGAAAATCCTCAAGATGTGCGTTATCCATGATTTGGGCGAAGCCATCCACGGCGATATCCCG
GCGGTCAGCCAGGCGGCCTTTCCCAACAAGGGCGAACAGGAGCGACTCGACCTGCTGCTGTTGGCCCAGTCCCTGGACAG
CCCGCTGAAAACCGAAATCCTGACGTTGTGGGATGATTACGAGAACGCGCTTTCGCCGGAAGCAAAAGCGGTCAAGGCCA
TGGACAAACTGGAGACCCTGCTGCAGCACACCCAGGGGCTGAACCCTCCCGATTTCGACTACGCCTTCAACCTGGCCTAC
GGCAAAAAACACACGGATGCCGACCCCTTGTTCGAAGCATTGCGGGCATTGATCGATCGAGCGACAGAGCAAAGGCTTCA
CGCCGCCGAGTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20524.53 Da        Isoelectric Point: 7.8770

>AT53452 WP_046068823.1 NZ_CP011117:1282031-1282588 [Pseudomonas synxantha]
MPHSLLKPALPGIALRRWRLLHRVKQSHAAQLFNVTQSTISRWESGIQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRALQFTSPLTDLMGQSLWRFATQEIQLIEASLEHTGWRETQAPPALEFTTGSNDSSLVP
IRPSLCRWTRMTLSDGSAARLVETL

Download         Length: 558 bp

>AT53452 NZ_CP011117:1282031-1282588 [Pseudomonas synxantha]
ATGCCTCACTCCTTGCTCAAGCCTGCGCTGCCCGGCATTGCGCTGCGGCGATGGCGTTTGCTGCACCGCGTCAAGCAAAG
CCATGCGGCGCAGCTATTCAACGTCACGCAATCGACTATTTCGCGCTGGGAAAGTGGCATACAAGCAATGGATCCGGCTG
CGCACCAACAGCTTGAGCAACTGTTGGCAGCCCGGCTTGATGCAGCCGCCGACCAGGCATTGGCCCGGCTGGTCAGTGAG
AGTTCGCAAGCGATGCACCTGGTATGCGACCTGACGCACCGCCTGCTCGCATGCTCGCCCTCCCGTGCACTCCAATTCAC
CAGCCCGCTCACCGACCTTATGGGCCAGTCGCTGTGGCGCTTCGCAACCCAGGAAATCCAGCTGATCGAAGCCAGCCTGG
AGCACACCGGCTGGCGCGAAACCCAGGCCCCCCCAGCCCTTGAGTTCACCACTGGAAGCAACGATTCCAGCCTCGTGCCG
ATACGCCCAAGCCTGTGTCGGTGGACGCGCATGACCCTGAGCGATGGCAGCGCCGCGCGCCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References