Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 5399231..5399784 Replicon chromosome
Accession NZ_CP011112
Organism Luteipulveratus mongoliensis strain MN07-A0370

Toxin (Protein)


Gene name relE Uniprot ID A0A0K1JP27
Locus tag VV02_RS25680 Protein ID WP_052596320.1
Coordinates 5399231..5399509 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0K1JPF6
Locus tag VV02_RS25685 Protein ID WP_052596322.1
Coordinates 5399506..5399784 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VV02_RS25665 5395394..5397463 + 2070 WP_052596317.1 hypothetical protein -
VV02_RS25670 5397474..5398067 + 594 WP_052596318.1 alpha/beta hydrolase -
VV02_RS25675 5398181..5399206 + 1026 WP_052596319.1 DNA polymerase IV -
VV02_RS25680 5399231..5399509 - 279 WP_052596320.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VV02_RS25685 5399506..5399784 - 279 WP_052596322.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
VV02_RS25690 5399853..5401442 - 1590 WP_157063570.1 polyprenol phosphomannose-dependent alpha 1,6 mannosyltransferase MptB -
VV02_RS25695 5401439..5402134 - 696 WP_052596327.1 glycosyltransferase family 2 protein -
VV02_RS25700 5402147..5403022 - 876 WP_052596329.1 hypothetical protein -
VV02_RS25705 5403079..5404491 - 1413 WP_052596331.1 DUF2079 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10656.17 Da        Isoelectric Point: 10.6716

>T53399 WP_052596320.1 NZ_CP011112:c5399509-5399231 [Luteipulveratus mongoliensis]
MSNDRPWRVELTSPAQQDLGRIPPRYAVAIVEFITAVLPTNPHRLGKPMHNELEGLHGARRGDYRVLYRIDGDGRTVYVH
RIDHRGRVYKAR

Download         Length: 279 bp

>T53399 NZ_CP011112:c5399509-5399231 [Luteipulveratus mongoliensis]
ATGAGCAACGACCGACCATGGCGGGTTGAACTCACCTCGCCGGCGCAACAGGACCTTGGTCGGATCCCGCCCCGATACGC
AGTGGCGATCGTGGAGTTCATCACGGCCGTGCTGCCGACCAATCCGCACCGGCTCGGGAAGCCGATGCACAACGAGCTCG
AAGGATTGCACGGTGCACGCCGCGGCGACTACCGCGTGCTCTATCGCATCGACGGCGACGGTCGCACTGTGTATGTGCAC
CGCATCGATCACCGCGGTCGCGTCTACAAGGCCCGCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9990.08 Da        Isoelectric Point: 4.3431

>AT53399 WP_052596322.1 NZ_CP011112:c5399784-5399506 [Luteipulveratus mongoliensis]
MKTLSISAAKAKLNELVDDAQRTHEHVTLTKNGSPAAVMVSADEWEAIQETLFWQSQPGIREDVAQAEQDISEGNTVGAD
EVRARYGLPPLG

Download         Length: 279 bp

>AT53399 NZ_CP011112:c5399784-5399506 [Luteipulveratus mongoliensis]
ATGAAGACCTTGTCGATCAGTGCTGCGAAGGCGAAGCTCAATGAGCTCGTCGACGATGCGCAACGCACGCACGAGCACGT
CACGTTGACCAAGAACGGGTCGCCGGCGGCCGTGATGGTGTCGGCCGATGAGTGGGAAGCGATTCAGGAGACGTTGTTCT
GGCAGTCGCAGCCCGGGATCCGGGAGGACGTGGCGCAAGCCGAACAGGACATCTCCGAGGGCAACACCGTCGGCGCTGAT
GAGGTGCGCGCTCGCTACGGGCTTCCGCCGCTCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K1JP27

Antitoxin

Source ID Structure
AlphaFold DB A0A0K1JPF6

References