53391

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 5677211..5677749 Replicon chromosome
Accession NZ_CP011110
Organism Pseudomonas chlororaphis strain PCL1606

Toxin (Protein)


Gene name relE Uniprot ID A0A0C5EEU9
Locus tag PCL1606_RS25530 Protein ID WP_044461181.1
Coordinates 5677211..5677489 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D5Y6U6
Locus tag PCL1606_RS25535 Protein ID WP_045885683.1
Coordinates 5677486..5677749 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCL1606_RS25510 5672670..5673572 + 903 WP_045885680.1 glycine betaine ABC transporter substrate-binding protein -
PCL1606_RS25515 5673586..5674239 + 654 WP_044461184.1 ABC transporter permease -
PCL1606_RS25520 5674236..5675393 + 1158 WP_044461183.1 ABC transporter ATP-binding protein -
PCL1606_RS25525 5675973..5677136 + 1164 WP_044461182.1 type III PLP-dependent enzyme -
PCL1606_RS25530 5677211..5677489 - 279 WP_044461181.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PCL1606_RS25535 5677486..5677749 - 264 WP_045885683.1 ribbon-helix-helix domain-containing protein Antitoxin
PCL1606_RS25540 5677806..5678591 - 786 WP_045885686.1 sel1 repeat family protein -
PCL1606_RS25545 5678595..5679275 - 681 WP_044461178.1 Fe2+-dependent dioxygenase -
PCL1606_RS25550 5679481..5681760 + 2280 Protein_5116 TonB-dependent siderophore receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10781.50 Da        Isoelectric Point: 10.5216

>T53391 WP_044461181.1 NZ_CP011110:c5677489-5677211 [Pseudomonas chlororaphis]
VRALKWTSKALSDLARLFEFLAPVNRSAAARTVQSLTRAPETLLANPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQGMTL
YILRVWHVREDR

Download         Length: 279 bp

>T53391 NZ_CP011110:c5677489-5677211 [Pseudomonas chlororaphis]
GTGAGGGCGTTGAAGTGGACGAGCAAGGCGCTATCGGACCTGGCTCGGCTGTTTGAGTTTCTCGCTCCCGTGAATCGCTC
GGCCGCTGCCCGAACGGTGCAATCCCTGACACGAGCCCCGGAGACCCTGCTGGCCAATCCGCGTATCGGCGAGCAGTTGG
AGGAGTTTCAACCTCGCGATGTCCGGCGTTTGTTGGTAGGGCCCTACGAGATGCGTTATGAGATTCAGGGGATGACGCTC
TATATCCTGCGGGTGTGGCACGTGCGGGAAGACCGATAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9741.05 Da        Isoelectric Point: 4.6239

>AT53391 WP_045885683.1 NZ_CP011110:c5677749-5677486 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDAGQVIDHQAVQAWAESLMND
EPLPVPK

Download         Length: 264 bp

>AT53391 NZ_CP011110:c5677749-5677486 [Pseudomonas chlororaphis]
ATGACTGCCACTAAAGTGCTGACGGCCCATGTGCCTCTGGAGCTGGCCGACAAGGTCGACCAGATGGCCTCCCGGCTGGA
GCGTTCGCGCGGCTGGATCGTCAAGCAGGCGCTGGTGGCCTGGGTCGACCAGGAAGAGGAGCGCAGCCGCCTGACGCACG
AGGCCCTGGCCGATGTGGACGCGGGGCAGGTCATCGACCATCAGGCCGTTCAGGCATGGGCCGAGAGCCTGATGAATGAT
GAGCCTTTACCGGTGCCCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5EEU9

Antitoxin

Source ID Structure
AlphaFold DB A0A0D5Y6U6

References