Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 3791833..3793115 | Replicon | chromosome |
| Accession | NZ_CP011110 | ||
| Organism | Pseudomonas chlororaphis strain PCL1606 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A0C5E409 |
| Locus tag | PCL1606_RS16775 | Protein ID | WP_044462754.1 |
| Coordinates | 3791833..3792417 (-) | Length | 195 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | PCL1606_RS16780 | Protein ID | WP_045883630.1 |
| Coordinates | 3792543..3793115 (-) | Length | 191 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PCL1606_RS16750 | 3787275..3788180 | - | 906 | WP_045883617.1 | NAD-binding protein | - |
| PCL1606_RS16755 | 3788666..3789019 | + | 354 | WP_044462758.1 | hypothetical protein | - |
| PCL1606_RS16760 | 3789071..3790111 | - | 1041 | WP_045883621.1 | membrane protein | - |
| PCL1606_RS16765 | 3790108..3791097 | - | 990 | WP_045883624.1 | hypothetical protein | - |
| PCL1606_RS16770 | 3791273..3791785 | - | 513 | WP_045883629.1 | N-acetyltransferase | - |
| PCL1606_RS16775 | 3791833..3792417 | - | 585 | WP_044462754.1 | HD domain-containing protein | Toxin |
| PCL1606_RS16780 | 3792543..3793115 | - | 573 | WP_045883630.1 | helix-turn-helix domain-containing protein | Antitoxin |
| PCL1606_RS16785 | 3793203..3793904 | - | 702 | WP_045883632.1 | NAD(P)H-dependent oxidoreductase | - |
| PCL1606_RS16790 | 3793946..3795361 | - | 1416 | WP_045883634.1 | aldehyde dehydrogenase family protein | - |
| PCL1606_RS16795 | 3795354..3796544 | - | 1191 | WP_045883636.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 195 a.a. Molecular weight: 21839.60 Da Isoelectric Point: 5.8869
>T53386 WP_044462754.1 NZ_CP011110:c3792417-3791833 [Pseudomonas chlororaphis]
MTDETLNGKLAFLREAERLKDVLRSAHTSGGRQESTAEHSWRLCLMVLVFEQELAGLDLLKLLKLCVIHDLGEAIHGDIP
AVSQAAHPHKSEQERADLLQLTRSLPPSLRASLLGLWEEYEAAATPEAQAVKALDKLETLLQHNQGRNPDDFDYGFNLGY
GRRYTSATPLFQALRERVDEDTRQRLRQQASNQA
MTDETLNGKLAFLREAERLKDVLRSAHTSGGRQESTAEHSWRLCLMVLVFEQELAGLDLLKLLKLCVIHDLGEAIHGDIP
AVSQAAHPHKSEQERADLLQLTRSLPPSLRASLLGLWEEYEAAATPEAQAVKALDKLETLLQHNQGRNPDDFDYGFNLGY
GRRYTSATPLFQALRERVDEDTRQRLRQQASNQA
Download Length: 585 bp
>T53386 NZ_CP011110:c3792417-3791833 [Pseudomonas chlororaphis]
ATGACTGACGAAACCCTCAACGGCAAACTGGCGTTCCTGCGCGAAGCGGAACGGCTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCGGCGGCCGCCAGGAAAGCACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGTGCTGGTTTTCGAGCAGGAAC
TGGCCGGCCTGGACCTGCTGAAACTGCTCAAGCTGTGTGTGATCCATGACCTGGGCGAGGCGATCCACGGCGATATCCCG
GCGGTGAGCCAGGCGGCCCATCCGCACAAGAGCGAGCAGGAACGCGCCGACCTGTTGCAGTTGACCCGTAGCCTGCCGCC
CTCGCTGCGCGCGAGCCTGCTCGGTTTGTGGGAAGAATATGAAGCCGCCGCTACGCCAGAGGCGCAGGCGGTCAAGGCGC
TGGACAAGCTGGAGACCCTGCTGCAACACAACCAGGGGCGCAACCCGGACGATTTCGACTACGGCTTCAACCTGGGTTAC
GGTCGCCGCTACACCAGCGCCACGCCGCTGTTCCAGGCGCTGCGCGAACGGGTCGACGAAGACACCCGGCAGCGCCTGCG
GCAGCAGGCATCGAACCAAGCCTGA
ATGACTGACGAAACCCTCAACGGCAAACTGGCGTTCCTGCGCGAAGCGGAACGGCTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCGGCGGCCGCCAGGAAAGCACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGTGCTGGTTTTCGAGCAGGAAC
TGGCCGGCCTGGACCTGCTGAAACTGCTCAAGCTGTGTGTGATCCATGACCTGGGCGAGGCGATCCACGGCGATATCCCG
GCGGTGAGCCAGGCGGCCCATCCGCACAAGAGCGAGCAGGAACGCGCCGACCTGTTGCAGTTGACCCGTAGCCTGCCGCC
CTCGCTGCGCGCGAGCCTGCTCGGTTTGTGGGAAGAATATGAAGCCGCCGCTACGCCAGAGGCGCAGGCGGTCAAGGCGC
TGGACAAGCTGGAGACCCTGCTGCAACACAACCAGGGGCGCAACCCGGACGATTTCGACTACGGCTTCAACCTGGGTTAC
GGTCGCCGCTACACCAGCGCCACGCCGCTGTTCCAGGCGCTGCGCGAACGGGTCGACGAAGACACCCGGCAGCGCCTGCG
GCAGCAGGCATCGAACCAAGCCTGA
Antitoxin
Download Length: 191 a.a. Molecular weight: 20987.20 Da Isoelectric Point: 7.7426
>AT53386 WP_045883630.1 NZ_CP011110:c3793115-3792543 [Pseudomonas chlororaphis]
MAASFPPSPLLSTTHLGVALRRWRLLHRVKQEHAAQLFKVAQSTISRWENGVQAMEPPEQARLEQLLAARLHAAADQALA
RLVNDNPRPVHLVCDLTHRLLACSPARAAQFSVPLGELLGESLWRFCTAEIVRQEAALDDLGWRSLLAPPSLEFVSGAND
CAIVPIHQSLCRWTRLNLSDGTAARLVETL
MAASFPPSPLLSTTHLGVALRRWRLLHRVKQEHAAQLFKVAQSTISRWENGVQAMEPPEQARLEQLLAARLHAAADQALA
RLVNDNPRPVHLVCDLTHRLLACSPARAAQFSVPLGELLGESLWRFCTAEIVRQEAALDDLGWRSLLAPPSLEFVSGAND
CAIVPIHQSLCRWTRLNLSDGTAARLVETL
Download Length: 573 bp
>AT53386 NZ_CP011110:c3793115-3792543 [Pseudomonas chlororaphis]
ATGGCTGCCTCTTTCCCGCCGTCGCCGTTGCTGTCGACCACTCACCTGGGCGTCGCGCTCAGGCGCTGGCGCCTGTTGCA
CCGGGTCAAGCAGGAGCATGCGGCGCAGTTGTTCAAGGTCGCCCAGTCGACCATTTCCCGTTGGGAAAACGGCGTGCAGG
CCATGGAGCCGCCGGAGCAGGCGCGGCTCGAACAATTGCTGGCGGCCCGCCTGCACGCGGCGGCCGACCAGGCCCTGGCG
CGGCTGGTCAACGACAACCCGCGGCCCGTGCATTTGGTGTGCGACCTGACCCACCGCCTGCTGGCTTGTTCGCCGGCGCG
GGCGGCGCAGTTCTCGGTGCCGCTCGGCGAGCTGCTGGGCGAATCGCTGTGGCGCTTTTGCACGGCCGAGATCGTCCGCC
AGGAGGCGGCGCTGGACGATCTGGGCTGGCGCAGCCTGCTGGCGCCGCCTTCCCTGGAGTTCGTCAGCGGGGCCAACGAT
TGCGCCATCGTGCCGATCCATCAGAGCCTCTGCCGCTGGACTCGCCTGAACCTGTCCGACGGCACGGCGGCGCGTCTGGT
GGAAACCCTCTGA
ATGGCTGCCTCTTTCCCGCCGTCGCCGTTGCTGTCGACCACTCACCTGGGCGTCGCGCTCAGGCGCTGGCGCCTGTTGCA
CCGGGTCAAGCAGGAGCATGCGGCGCAGTTGTTCAAGGTCGCCCAGTCGACCATTTCCCGTTGGGAAAACGGCGTGCAGG
CCATGGAGCCGCCGGAGCAGGCGCGGCTCGAACAATTGCTGGCGGCCCGCCTGCACGCGGCGGCCGACCAGGCCCTGGCG
CGGCTGGTCAACGACAACCCGCGGCCCGTGCATTTGGTGTGCGACCTGACCCACCGCCTGCTGGCTTGTTCGCCGGCGCG
GGCGGCGCAGTTCTCGGTGCCGCTCGGCGAGCTGCTGGGCGAATCGCTGTGGCGCTTTTGCACGGCCGAGATCGTCCGCC
AGGAGGCGGCGCTGGACGATCTGGGCTGGCGCAGCCTGCTGGCGCCGCCTTCCCTGGAGTTCGTCAGCGGGGCCAACGAT
TGCGCCATCGTGCCGATCCATCAGAGCCTCTGCCGCTGGACTCGCCTGAACCTGTCCGACGGCACGGCGGCGCGTCTGGT
GGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|