53383

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 783701..784290 Replicon chromosome
Accession NZ_CP011110
Organism Pseudomonas chlororaphis strain PCL1606

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PCL1606_RS03740 Protein ID WP_045881100.1
Coordinates 783701..784000 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PCL1606_RS03745 Protein ID WP_045881101.1
Coordinates 783997..784290 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCL1606_RS03710 779317..779559 - 243 WP_044465286.1 exodeoxyribonuclease VII small subunit -
PCL1606_RS31080 779755..779910 + 156 WP_155736162.1 hypothetical protein -
PCL1606_RS03715 780004..780246 + 243 WP_148558614.1 hypothetical protein -
PCL1606_RS03720 780524..781615 + 1092 WP_045881098.1 nitrite reductase, copper-containing -
PCL1606_RS03725 781681..781980 + 300 WP_044465283.1 ArsR family transcriptional regulator -
PCL1606_RS03730 782038..783048 + 1011 WP_171820092.1 zinc-binding dehydrogenase -
PCL1606_RS03735 783073..783522 - 450 WP_044465281.1 DUF3828 domain-containing protein -
PCL1606_RS03740 783701..784000 + 300 WP_045881100.1 hypothetical protein Toxin
PCL1606_RS03745 783997..784290 + 294 WP_045881101.1 putative addiction module antidote protein Antitoxin
PCL1606_RS03750 784359..784751 - 393 WP_045881102.1 hypothetical protein -
PCL1606_RS03755 785120..786007 - 888 WP_045881103.1 LysR family transcriptional regulator -
PCL1606_RS03760 786134..787324 + 1191 WP_045881104.1 serine hydrolase -
PCL1606_RS03765 787519..788682 + 1164 WP_045886693.1 acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(12-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11241.94 Da        Isoelectric Point: 9.9933

>T53383 WP_045881100.1 NZ_CP011110:783701-784000 [Pseudomonas chlororaphis]
MVEIKQTATFMEWERRLRDSRARAAIAARIFRLANGLAGDVFPVGEGVSELCIHYGPGYRVYFQYRVLQLVILLCGGDKS
HQSRDIERARSLARGWSPS

Download         Length: 300 bp

>T53383 NZ_CP011110:783701-784000 [Pseudomonas chlororaphis]
ATGGTGGAAATCAAACAGACCGCGACCTTCATGGAGTGGGAACGCAGGCTCAGGGATTCCAGGGCCAGGGCGGCGATTGC
AGCGCGTATCTTTCGCTTGGCCAACGGCCTTGCCGGGGATGTTTTTCCGGTGGGCGAGGGCGTCAGCGAACTTTGCATCC
ATTACGGGCCGGGTTACCGGGTGTACTTCCAGTACCGTGTCCTGCAACTCGTCATCCTGCTGTGCGGCGGCGACAAAAGT
CACCAGAGCCGCGATATCGAACGGGCCAGGAGCCTGGCCCGTGGTTGGAGCCCATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10396.92 Da        Isoelectric Point: 5.6642

>AT53383 WP_045881101.1 NZ_CP011110:783997-784290 [Pseudomonas chlororaphis]
MNEPLLDYDPASALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSEKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp

>AT53383 NZ_CP011110:783997-784290 [Pseudomonas chlororaphis]
ATGAACGAACCACTATTGGACTATGACCCCGCCTCGGCCCTGCGTGACCCGCAAGCCATCGCCCTGTTCATGGCAGACGC
CTTCGAAACCGGCGACGCCGGCTACATCGCCAAGGCCCTGGGCGTGGTGGCCCGCGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGCCTGTCTCGCGAGCAGCTGTACCGCTCGTTCAGCGAAAAGGGCAACCCGACCCTCAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGCCTGGACATGACGGCGCGGGTGCATGGAGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References