Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3289002..3289501 Replicon chromosome
Accession NZ_CP011102
Organism Listeria weihenstephanensis strain WS 4560

Toxin (Protein)


Gene name relE Uniprot ID W7CZ75
Locus tag UE46_RS15730 Protein ID WP_036061391.1
Coordinates 3289002..3289271 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W7CML7
Locus tag UE46_RS15735 Protein ID WP_036061389.1
Coordinates 3289268..3289501 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UE46_RS15725 3288070..3288696 - 627 WP_036061393.1 NAD(P)H-binding protein -
UE46_RS15730 3289002..3289271 - 270 WP_036061391.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
UE46_RS15735 3289268..3289501 - 234 WP_036061389.1 toxin-antitoxin system antitoxin component Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-70)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10449.14 Da        Isoelectric Point: 10.5472

>T53350 WP_036061391.1 NZ_CP011102:c3289271-3289002 [Listeria weihenstephanensis]
MSYQIKTTRQFEKQLSKLDRQASRTILRWLSKHIDGADNPRISGKALLGNYAGQWRYRIGDYRVICKIVDDELIVLALEV
GHRKQVYKK

Download         Length: 270 bp

>T53350 NZ_CP011102:c3289271-3289002 [Listeria weihenstephanensis]
ATGAGCTACCAGATTAAGACAACACGTCAATTCGAAAAGCAGTTATCCAAATTAGATAGGCAGGCTAGTCGTACGATTTT
AAGATGGTTATCGAAACATATTGACGGCGCGGATAATCCGAGGATAAGTGGCAAGGCGTTGCTAGGTAACTACGCTGGTC
AGTGGAGATATCGTATAGGAGATTATCGAGTTATTTGTAAAATTGTTGACGATGAGTTAATTGTACTCGCTTTAGAAGTT
GGTCATAGGAAACAAGTCTACAAAAAGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8892.84 Da        Isoelectric Point: 3.9156

>AT53350 WP_036061389.1 NZ_CP011102:c3289501-3289268 [Listeria weihenstephanensis]
MATITVRVSDVEKQFLDEMAKFEGKSLSDLLKTTTLESLEDEYDARVADYAYEEYLKKPESRPLSELMSEYGLDDDE

Download         Length: 234 bp

>AT53350 NZ_CP011102:c3289501-3289268 [Listeria weihenstephanensis]
ATGGCGACAATAACAGTTCGTGTTTCGGATGTAGAGAAACAATTTTTGGATGAAATGGCGAAGTTTGAAGGAAAGAGTTT
ATCGGACTTACTGAAGACAACAACACTCGAATCATTAGAAGATGAATATGATGCTCGGGTGGCTGATTATGCCTATGAAG
AATATCTAAAGAAGCCTGAATCACGTCCTTTATCTGAACTTATGTCAGAATACGGATTGGATGACGATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S7FY19

Antitoxin

Source ID Structure
AlphaFold DB A0A1S7FY50

References