53322

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2753911..2755631 Replicon chromosome
Accession NZ_CP011078
Organism Yersinia ruckeri strain Big Creek 74

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag UGYR_RS12480 Protein ID WP_045844433.1
Coordinates 2753911..2754567 (+) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag UGYR_RS12485 Protein ID WP_038245756.1
Coordinates 2754564..2755631 (+) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UGYR_RS12450 2749127..2750071 - 945 WP_038275265.1 hypothetical protein -
UGYR_RS12455 2750586..2751845 + 1260 Protein_2407 integrase arm-type DNA-binding domain-containing protein -
UGYR_RS12460 2752019..2752273 + 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
UGYR_RS12465 2752263..2752553 + 291 WP_038275268.1 type II toxin-antitoxin system RelE/ParE family toxin -
UGYR_RS12470 2752817..2753239 + 423 WP_052690340.1 restriction endonuclease subunit S -
UGYR_RS12475 2753333..2753908 + 576 WP_045844432.1 DUF4433 domain-containing protein -
UGYR_RS12480 2753911..2754567 + 657 WP_045844433.1 DUF4433 domain-containing protein Toxin
UGYR_RS12485 2754564..2755631 + 1068 WP_038245756.1 macro domain-containing protein Antitoxin
UGYR_RS17065 2755652..2755918 + 267 Protein_2414 hypothetical protein -
UGYR_RS17070 2755937..2756335 - 399 Protein_2415 DDE-type integrase/transposase/recombinase -
UGYR_RS12490 2756340..2756630 + 291 Protein_2416 transposase -
UGYR_RS17510 2756644..2756742 - 99 Protein_2417 transposase -
UGYR_RS17515 2756778..2756906 - 129 Protein_2418 helix-turn-helix domain-containing protein -
UGYR_RS12495 2757056..2757286 + 231 WP_073990333.1 DUF4942 domain-containing protein -
UGYR_RS12500 2757361..2757756 + 396 WP_038245317.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
UGYR_RS12505 2757749..2758699 + 951 WP_045844434.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
UGYR_RS17325 2759072..2759356 + 285 WP_038245319.1 antirestriction protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2727395..2755631 28236
- flank IS/Tn - - 2756382..2756630 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25216.69 Da        Isoelectric Point: 6.6007

>T53322 WP_045844433.1 NZ_CP011078:2753911-2754567 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLTNYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGARLQLEQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp

>T53322 NZ_CP011078:2753911-2754567 [Yersinia ruckeri]
GTGGCCTATGACTACAGCACTAGCCTCAACCCGGAAAAAGCCTTGATCTGGCGCATTGTCCATCGGGACAATATTCCGTG
GATACTGGACAACGGTCTGCACTGTGGCAACAGTCCGGTGCAGGCGGAAGACTGGATTAATATCGGTAACCCGGAGCTTA
TCGACAAACGTGCCGGACATCTGGTGCCAACCGGAATGCGGGGGACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCGATGCTGATGAATATCCGCAGCGGACGTGGCGGCATTAAGCAACGCCCCAATGAGGAGATCGTTATTCTGGT
CAGTAGCCTGCGAAACATGGTGGCGCAAAATGTTTCCTTCGTGTTTACCGATAGCCACGCATATTATAACCTGACTAATT
ACTTTACCGAGCTGGACAGTCTGAACCAGATCGATTGGCCCATTCTACAAGCGCGGGATTTCCGTCGCGATCAGGACGAT
TTGGCCAAGTTCGAACGCTATCAGGCAGAGGCGTTAATTTGGAAGCACTGCCCAATAGCGCTGCTTGGCGGGATGATTTG
TTACAACGATGGCGCCAGGTTACAATTAGAGCAGTGGTTGTCGCAACGCAATCTGTCAATGCCCGTTCACGCGCGGGCTG
GGTGGTACTTCTCATGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40846.27 Da        Isoelectric Point: 6.6976

>AT53322 WP_038245756.1 NZ_CP011078:2754564-2755631 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIKEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp

>AT53322 NZ_CP011078:2754564-2755631 [Yersinia ruckeri]
ATGATTACATTTACACAAGGCAATTTACTGGATGCGCCCGTAGAAGCACTAGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTGATGTTCAAAGAGCGCTTCCCCGTCAATATGAAAGCCTATGCTCTCGCCTGCAAACATAAGC
AGGTAATGACAGGTAAAATGTTTATTACCGAAACCGGCGAACTGATGGGGCCTCGCTGGATTGTCAACTTCCCAACTAAA
CAACACTGGCGCGCAGACTCCCGCATGGAGTGGGTTGAAGACGGCTTGCAGGATTTACGCCGCTTTTTGATCAAAGAGAA
AGTGCAATCTATCGCCATTCCCCCACTGGGGGCGGGTAACGGCGGCCTGAATTGGTCGGACGTTCGGATGCGGATTGAAT
CTGCGCTGGGCGACCTTCAGGACACGGAAATTCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGTACC
GGCGTAAAAAAGCTCACTCCCGCCAGAGCGCTGATTGCTGAACTGGTGCGCCGCTACTGGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCCATTGAACAGCATCAGCAGGAAGATGTGCTGAAACTGC
GGTTTGAGGCGCACTATTACGGCCCCTACGCCCCCAACCTTAACCATCTGCTTAACGCGCTAGATGGCACGTATCTGAAA
GCAGAGAAACGCATCCCGGACACCCAGCCGCTGGATGTGATCTGGTTTAATGATCAGGAAAAAGAACACATCAACCTCTG
GCTGAACAACGAGGCCAAAGAGTGGCTACCGGCGCTTGAGCAGGTCAGTCAGTTGATTGACGGCTTTGAATCGCCGTTTG
GTCTGGAGCTGCTGGCAACCGTTGACTGGCTGCTGACCCGAGGAAAATGCCAGCCCACGCTGGATTCCGTGAAAGAGGGG
CTGCACCAGTGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTCTTTGACGACAAGAATCTGCAATTTGCCAT
CAACCGCGTGATGGAGTTCCATTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References