Detailed information of TA system TA053319

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 1532823..1533492
• Replicon: chromosome
• Accession: NZ_CP011078
• Organism: Yersinia ruckeri strain Big Creek 74

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: UGYR_RS07075
• Protein ID: WP_045844283.1
• Coordinates: 1532823..1533245 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: UGYR_RS07080
• Protein ID: WP_004719196.1
• Coordinates: 1533226..1533492 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
UGYR_RS07055	1528662..1530395	-	1734	WP_045844282.1	single-stranded-DNA-specific exonuclease RecJ	-
UGYR_RS07060	1530402..1531118	-	717	WP_004719192.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
UGYR_RS07065	1531150..1532049	-	900	WP_004719193.1	site-specific tyrosine recombinase XerD	-
UGYR_RS07070	1532157..1532675	+	519	WP_038241022.1	flavodoxin FldB	-
UGYR_RS07075	1532823..1533245	-	423	WP_045844283.1	protein YgfX	Toxin
UGYR_RS07080	1533226..1533492	-	267	WP_004719196.1	FAD assembly factor SdhE	Antitoxin
UGYR_RS07085	1533786..1534778	+	993	WP_045844284.1	tRNA-modifying protein YgfZ	-
UGYR_RS07090	1534917..1535582	-	666	WP_175537887.1	hemolysin III family protein	-
UGYR_RS17240	1535899..1536239	+	341	Protein_1382	HD domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (7-79)

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 16520.52 Da
• Isoelectric Point: 11.3725

>T53319 WP_045844283.1 NZ_CP011078:c1533245-1532823 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGRRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Nucleotide

• Length: 423 bp

>T53319 NZ_CP011078:c1533245-1532823 [Yersinia ruckeri]
GTGGCCCAGTGGCGATGTGATCTGCGGGTTTCATGGCGCACCCAACTTTTCTCACTATTGGTACACGGTGTTCTGGTATT
ACTGACACTGGTGGTACCTTGGCCTGACGGATTTACTCCGCTATGGCTTATATTGCTGACGCTGGTGGTGTTTGAATGCA
TTCGCAGCCAGAAGAACATTACCTCTCGACAGGGAGAGATCCGGCTTAAAGCGGGAAATCTGTTGATTTGGAAGTGGCAA
GAGTGGACGTTGGTGCGGCCGCCGTGGATTACCCGCTACGGCGTATTATTATCGTTACAAGGCGCTGGCCGCCGCCGCCG
AAAACGTATTTGGCTAGCCTCCGACAGCATGTCGGAAGAAAAATGGCGCGAGTTGTGTCTGATATTACGACATACTTTTG
ATTCTGCGGCAGGCCGTGAGTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10532.09 Da
• Isoelectric Point: 6.7185

>AT53319 WP_004719196.1 NZ_CP011078:c1533492-1533226 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Nucleotide

• Length: 267 bp

>AT53319 NZ_CP011078:c1533492-1533226 [Yersinia ruckeri]
ATGGAAATTGATAACAAAGCCCGAATCCATTGGGCATGCCGCCGGGGTATGCGTGAACTGGATATCTCCATAATGCCATT
TTTCGAACATGAATATGACACGCTAAACGATAATGATAAGCGCGTATTTATCCGCTTGCTGACGAGTGATGATCCTGATT
TATTCAATTGGTTGATGAACCACGGCGAGCCGCAGGATAGCGAACTGAAACGAATGGTTAAACTGATTCAGACACGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA