Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 197853..198523 Replicon chromosome
Accession NZ_CP011072
Organism Azoarcus sp. CIB

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AzCIB_RS00775 Protein ID WP_050414142.1
Coordinates 198098..198523 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag AzCIB_RS00770 Protein ID WP_050414141.1
Coordinates 197853..198101 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AzCIB_RS00765 194052..197807 + 3756 WP_083447116.1 exodeoxyribonuclease V subunit beta -
AzCIB_RS00770 197853..198101 + 249 WP_050414141.1 toxin-antitoxin system Antitoxin
AzCIB_RS00775 198098..198523 + 426 WP_050414142.1 type II toxin-antitoxin system VapC family toxin Toxin
AzCIB_RS00780 198557..200821 + 2265 WP_050414143.1 exodeoxyribonuclease V subunit alpha -
AzCIB_RS00785 200852..202396 - 1545 WP_050414144.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15828.01 Da        Isoelectric Point: 4.9593

>T53294 WP_050414142.1 NZ_CP011072:198098-198523 [Azoarcus sp. CIB]
MILLDTNVLSALMQQQPDERVVVWLDEQPAESVWISSVTLFEARYGLALLAPGRRRAALQERFDLLVREDLENRVLLFDA
SAAAYAAELAAERRNAGRPVDMRDTFIAGIALSRRATIATRNTRHFDDLSVPVVNPWGEHA

Download         Length: 426 bp

>T53294 NZ_CP011072:198098-198523 [Azoarcus sp. CIB]
ATGATCCTGCTCGACACCAATGTCCTGTCGGCGCTGATGCAGCAACAGCCGGACGAGCGCGTCGTCGTGTGGCTCGACGA
GCAACCGGCCGAATCGGTGTGGATCAGCAGCGTGACGCTGTTCGAGGCGCGCTACGGCCTGGCGCTGCTCGCACCGGGGC
GCCGCCGCGCAGCGCTGCAGGAGCGCTTCGACCTGCTCGTGCGCGAGGACCTCGAAAACCGCGTGCTGCTCTTCGACGCC
AGTGCCGCCGCCTACGCCGCCGAGCTCGCGGCCGAGCGCCGCAATGCCGGCCGCCCGGTCGACATGCGCGACACCTTCAT
TGCCGGTATCGCGCTGTCGCGGCGTGCGACGATTGCGACCCGCAACACCCGGCACTTCGACGACCTGTCGGTGCCGGTCG
TGAATCCCTGGGGCGAGCATGCGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9018.31 Da        Isoelectric Point: 5.7395

>AT53294 WP_050414141.1 NZ_CP011072:197853-198101 [Azoarcus sp. CIB]
MAQVVVRNLEEEVKAGLKARAGRHGWSMEEEVRQILRRAVIEEDAARPRLGSRIAARFAGAGLTEPLPELHGEGIAPMEF
GE

Download         Length: 249 bp

>AT53294 NZ_CP011072:197853-198101 [Azoarcus sp. CIB]
ATGGCACAAGTCGTTGTTCGCAATCTCGAGGAAGAGGTCAAGGCCGGTCTGAAGGCGCGCGCCGGCCGCCACGGCTGGAG
CATGGAGGAAGAGGTGCGGCAGATCCTGCGGCGTGCGGTGATCGAGGAGGACGCGGCGCGCCCGCGGCTGGGCTCGCGCA
TTGCCGCGCGCTTTGCCGGCGCCGGACTGACGGAACCCTTGCCCGAACTGCACGGCGAAGGGATCGCGCCGATGGAGTTC
GGTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References