53206

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 120908..122246 Replicon chromosome
Accession NZ_CP011037
Organism Pseudoalteromonas nigrifaciens strain KMM 661

Toxin (Protein)


Gene name sanaT Uniprot ID A0A379I3A9
Locus tag PNIG_RS17085 Protein ID WP_041454885.1
Coordinates 121296..122246 (+) Length 317 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID A0A1R4KHH7
Locus tag PNIG_RS17080 Protein ID WP_011329741.1
Coordinates 120908..121306 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PNIG_RS17060 116786..117262 + 477 WP_089369050.1 hypothetical protein -
PNIG_RS17065 117265..118398 + 1134 WP_089369051.1 DUF1570 domain-containing protein -
PNIG_RS17070 118781..119452 - 672 WP_089369052.1 hypothetical protein -
PNIG_RS17075 119596..120600 - 1005 WP_089369053.1 NERD domain-containing protein -
PNIG_RS17080 120908..121306 + 399 WP_011329741.1 hypothetical protein Antitoxin
PNIG_RS17085 121296..122246 + 951 WP_041454885.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
PNIG_RS17090 122410..123390 - 981 WP_086996885.1 SEC-C domain-containing protein -
PNIG_RS17095 123599..124549 - 951 WP_089369054.1 glutathione S-transferase family protein -
PNIG_RS17100 124625..125080 - 456 WP_058374694.1 DoxX family protein -
PNIG_RS17105 125225..126112 + 888 WP_089369321.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-300)

Antitoxin

Protein of unknown function DUF6088

(16-70)


Sequences

Toxin        


Download         Length: 317 a.a.        Molecular weight: 36104.57 Da        Isoelectric Point: 6.6082

>T53206 WP_041454885.1 NZ_CP011037:121296-122246 [Pseudoalteromonas nigrifaciens]
MLIDSDLFLDVADALGMGNPAIVEKDYYVVALLKLLSELSFDTHLLVFSGGTALTKSGIKTHRMSEDIDIKIIPTDVFAN
ISKTQKRKARKELHLQLLNAISLHNSFSVENRPTIYDEYRYQQIDIRYPQAHSKVPCLRPFIKLELIETLLYDQVVSRDI
CSLMNEVTQKPPEVALMGFSSIKSTQAEKLVSMLRRTASFARDNIRDDDPALIRHIYDTYYIQQAGLASASDVMSLVSKV
IAEDLTRYSNQHAEFMKSPIAELKFGLSLLQTNTLYEERFNQYVVPMVYGNNSLNWQQAFDVFKLYCNQVLNNIKL

Download         Length: 951 bp

>T53206 NZ_CP011037:121296-122246 [Pseudoalteromonas nigrifaciens]
ATGCTAATTGATAGTGACCTGTTTTTAGATGTTGCCGATGCTCTTGGTATGGGTAACCCTGCTATTGTTGAAAAAGATTA
TTATGTTGTTGCATTACTAAAACTACTTTCTGAATTGTCTTTTGATACGCACTTATTGGTTTTTTCTGGTGGTACCGCAT
TAACAAAGTCGGGCATTAAAACTCATCGAATGTCTGAAGACATTGATATTAAAATCATACCTACAGATGTGTTTGCTAAT
ATTTCAAAAACACAAAAAAGAAAGGCTAGGAAAGAGTTACATCTTCAATTACTTAATGCCATTAGTCTGCACAACTCTTT
TTCGGTAGAAAACCGCCCTACTATTTATGATGAATATCGTTATCAACAAATTGATATACGTTATCCTCAAGCACATTCAA
AAGTTCCATGCCTAAGGCCGTTTATTAAGTTAGAGCTGATAGAGACCTTGCTTTATGATCAAGTAGTGAGTAGAGATATA
TGTTCTTTAATGAATGAGGTCACTCAAAAGCCTCCTGAAGTTGCGCTAATGGGGTTTTCGAGTATTAAGAGTACACAAGC
GGAAAAGCTAGTCTCTATGTTGAGGCGAACAGCAAGTTTTGCGCGCGATAATATAAGAGATGATGATCCTGCATTAATAC
GCCATATTTATGATACGTATTATATTCAACAAGCTGGGCTTGCGAGTGCTTCTGACGTAATGTCTTTGGTAAGTAAAGTT
ATTGCGGAAGACTTAACGCGTTACTCAAACCAACACGCTGAATTTATGAAAAGTCCGATTGCTGAACTGAAGTTTGGCTT
AAGCTTACTACAAACCAATACATTATATGAAGAACGCTTTAACCAATATGTAGTACCTATGGTTTATGGCAATAATAGCC
TTAATTGGCAGCAAGCATTTGATGTATTTAAGTTATATTGCAATCAAGTGTTAAATAACATAAAGCTTTAG

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14701.93 Da        Isoelectric Point: 10.5773

>AT53206 WP_011329741.1 NZ_CP011037:120908-121306 [Pseudoalteromonas nigrifaciens]
MTIASKVTTRINRSKRYVFDRADFADIAGYDQVGRVLKKLVDNGHLLRIGYGLYTKARENRITGKLMPASPAGADGVILE
AIEKLGVDYKFDEFSQRSINGESLQIPASLKIITNNRFKRKIVVNNSAINAN

Download         Length: 399 bp

>AT53206 NZ_CP011037:120908-121306 [Pseudoalteromonas nigrifaciens]
ATGACAATAGCAAGTAAAGTAACAACAAGAATAAACCGCTCAAAGCGTTATGTTTTTGATCGTGCTGATTTTGCAGATAT
TGCTGGTTACGACCAAGTTGGCCGGGTATTAAAAAAGCTGGTTGATAATGGTCATTTATTGCGTATTGGTTATGGGCTTT
ACACTAAAGCGAGAGAAAATCGCATTACGGGTAAGTTAATGCCGGCATCTCCTGCGGGAGCTGATGGTGTTATATTAGAA
GCGATTGAAAAGCTAGGTGTTGACTACAAATTTGATGAGTTTTCACAACGTAGTATCAATGGTGAAAGCTTGCAAATTCC
AGCGTCTCTGAAAATAATTACAAATAATCGCTTTAAACGCAAAATTGTCGTAAATAATAGTGCTATTAATGCTAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A379I3A9

Antitoxin

Source ID Structure
AlphaFold DB A0A1R4KHH7

References