53200

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 5692008..5692527 Replicon chromosome
Accession NZ_CP011020
Organism Pseudomonas chlororaphis strain UFB2 isolate Soil

Toxin (Protein)


Gene name relE Uniprot ID A0A0G3GIV1
Locus tag VM99_RS24825 Protein ID WP_047739100.1
Coordinates 5692008..5692289 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0G3GQV7
Locus tag VM99_RS24830 Protein ID WP_047739101.1
Coordinates 5692279..5692527 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VM99_RS24795 5687245..5688009 - 765 WP_047739095.1 IclR family transcriptional regulator -
VM99_RS24800 5688286..5688675 - 390 WP_047739096.1 RidA family protein -
VM99_RS24805 5688701..5689492 - 792 WP_047739097.1 amino acid ABC transporter ATP-binding protein -
VM99_RS24810 5689489..5690151 - 663 WP_047739098.1 amino acid ABC transporter permease -
VM99_RS24815 5690161..5690823 - 663 WP_042731870.1 amino acid ABC transporter permease -
VM99_RS24820 5690878..5691726 - 849 WP_047739099.1 transporter substrate-binding domain-containing protein -
VM99_RS24825 5692008..5692289 - 282 WP_047739100.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
VM99_RS24830 5692279..5692527 - 249 WP_047739101.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
VM99_RS24835 5692594..5694240 - 1647 WP_047739102.1 phospholipase -
VM99_RS24840 5694410..5695045 - 636 WP_199925071.1 VWA domain-containing protein -
VM99_RS24845 5695066..5696070 - 1005 WP_047739103.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10920.63 Da        Isoelectric Point: 10.2243

>T53200 WP_047739100.1 NZ_CP011020:c5692289-5692008 [Pseudomonas chlororaphis]
MTYELEFSDKAWKEWQKLGATLREQFKKKLEERLVNPHVQTDRLHGLGNAYKIKLRSAGYRLVYRVVDEVLVVTVIAVGK
RERGQVYDEAAKR

Download         Length: 282 bp

>T53200 NZ_CP011020:c5692289-5692008 [Pseudomonas chlororaphis]
ATGACCTATGAGTTGGAGTTTTCTGACAAAGCGTGGAAGGAGTGGCAAAAGCTGGGAGCAACGCTAAGAGAGCAGTTCAA
AAAGAAGCTTGAAGAGCGACTGGTAAATCCGCATGTCCAGACCGACCGTCTACACGGTTTGGGCAATGCCTATAAAATCA
AGCTGCGCAGCGCAGGCTATCGGCTGGTTTATCGTGTGGTGGACGAAGTACTGGTCGTTACGGTGATTGCTGTTGGTAAG
CGTGAGCGCGGTCAAGTTTACGATGAGGCCGCCAAGCGGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8967.35 Da        Isoelectric Point: 4.4000

>AT53200 WP_047739101.1 NZ_CP011020:c5692527-5692279 [Pseudomonas chlororaphis]
MTHVVLSQVVASISELKKNPMGTVAAGGGLSVAILNRNEPAFYCVPAKEYEAMMDRLEDMELAALCRERENDPTIKVSLD
DL

Download         Length: 249 bp

>AT53200 NZ_CP011020:c5692527-5692279 [Pseudomonas chlororaphis]
ATGACGCATGTCGTACTTTCTCAAGTAGTCGCCAGCATCTCAGAACTCAAGAAAAATCCGATGGGTACCGTTGCGGCAGG
TGGAGGATTGTCCGTGGCGATCCTCAACCGTAACGAGCCGGCTTTTTATTGTGTCCCAGCCAAGGAGTATGAGGCCATGA
TGGACAGGCTGGAGGACATGGAGCTGGCTGCTCTTTGCCGCGAGCGTGAAAACGACCCAACGATCAAGGTTTCTCTCGAT
GACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0G3GIV1

Antitoxin

Source ID Structure
AlphaFold DB A0A0G3GQV7

References