Detailed information of TA system TA053138

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 985559..986442
• Replicon: chromosome
• Accession: NZ_CP010979
• Organism: Pseudomonas putida S13.1.2

Toxin (Protein)

• Gene name: -
• Uniprot ID: A0A0C5RT19
• Locus tag: N805_RS04450
• Protein ID: WP_028613241.1
• Coordinates: 986005..986442 (+)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: R9VFG2
• Locus tag: N805_RS04445
• Protein ID: WP_016487684.1
• Coordinates: 985559..986008 (+)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N805_RS04415	980794..981300	-	507	WP_028613247.1	sigma-70 family RNA polymerase sigma factor	-
N805_RS04420	981382..982005	-	624	WP_028613246.1	glutathione S-transferase	-
N805_RS04425	982204..982503	+	300	WP_028613245.1	DUF3077 domain-containing protein	-
N805_RS04430	982583..983305	+	723	WP_028613244.1	hypothetical protein	-
N805_RS04435	983598..984518	+	921	WP_028613243.1	LysR family transcriptional regulator	-
N805_RS04440	984689..985465	+	777	WP_028613242.1	SDR family oxidoreductase	-
N805_RS04445	985559..986008	+	450	WP_016487684.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
N805_RS04450	986005..986442	+	438	WP_028613241.1	RES family NAD+ phosphorylase	Toxin
N805_RS04455	986450..987604	-	1155	WP_028613240.1	aminotransferase class V-fold PLP-dependent enzyme	-
N805_RS04460	987799..988725	-	927	WP_046811294.1	LysR family transcriptional regulator	-
N805_RS04465	988864..990093	+	1230	WP_028613239.1	acyl-CoA dehydrogenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-138)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (33-91)

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 16033.41 Da
• Isoelectric Point: 6.2187

>T53138 WP_028613241.1 NZ_CP010979:986005-986442 [Pseudomonas putida S13.1.2]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPSGAMLEVLVHLEIDPEDFPTTMRLIRIELPDTVSQAQLPVLQ
PGWSAQPELTRALGNRFLDDCSALLLPVPSAIMPSTINYLFNPRHAQAQRAKIQVEDFTPDSRLF

Nucleotide

• Length: 438 bp

>T53138 NZ_CP010979:986005-986442 [Pseudomonas putida S13.1.2]
GTGATTTTGTGGCGTATCAGCGCCTATGCAGATTTGAGTGGCACTGGGGGGTTGCGTGTAAGCGGCCGGTGGCACCAGGC
GGGCCGGCCAGTGGTGTATGCCGCCACCAGCCCTTCCGGGGCCATGCTCGAGGTGCTGGTGCACCTGGAAATCGACCCCG
AGGATTTTCCTACCACCATGCGCCTGATCCGCATCGAATTGCCCGACACGGTTTCACAGGCGCAGTTGCCCGTCTTGCAG
CCCGGTTGGTCCGCTCAGCCTGAGTTGACCCGGGCGCTGGGCAATCGCTTTCTGGATGACTGCTCGGCATTGTTGCTGCC
GGTGCCGAGCGCGATCATGCCCAGTACCATCAACTACCTGTTCAACCCACGGCACGCGCAGGCGCAGCGTGCGAAAATCC
AGGTCGAGGATTTCACCCCGGACAGCCGCTTGTTCTAG

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 17096.64 Da
• Isoelectric Point: 6.1089

>AT53138 WP_016487684.1 NZ_CP010979:985559-986008 [Pseudomonas putida S13.1.2]
MLAEVLRDNGYHEYRARLQALLEIPELASDFEIHTRITHGFAATWLVKLTERGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEADKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Nucleotide

• Length: 450 bp

>AT53138 NZ_CP010979:985559-986008 [Pseudomonas putida S13.1.2]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCAGGCGCTGCTGGAAATACCCGAACT
CGCCAGTGACTTCGAAATCCACACCCGCATCACCCATGGTTTTGCTGCCACCTGGCTGGTGAAGCTGACCGAGCGTGGTG
TGTTCACGCCGGTGGAGCGGGACCAGATCATTCCCCTGCGCACCCTCAAAACCCGTATCGAGCGTGACCAGCCGCTGACC
GTGGAAGAGAGTGATCGGCTGTTCCGTTCAGCCCACATCACCGCCATGGCCGAAGCCGTGTTCGGTGAAGCGGACAAGGC
CAAGCGCTGGCTGTCCAAGCCCAAGGAACGCTTCTCGGGGCTGACGCCCATGCAGATGCTCACCACCCAGCAAGGCACCA
CTCAGGTGGAAGAGATGCTGCTGCAGATTGCCGAGGGCTTTGGCCTGTGA

Structures

Toxin

• AlphaFold DB: A0A0C5RT19

Antitoxin

• AlphaFold DB: R9VFG2