Detailed information of TA system TA053137

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 425657..426696
• Replicon: chromosome
• Accession: NZ_CP010979
• Organism: Pseudomonas putida S13.1.2

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: N805_RS01695
• Protein ID: WP_019470166.1
• Coordinates: 425657..426232 (-)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: A0A0C5RMW1
• Locus tag: N805_RS01700
• Protein ID: WP_019470167.1
• Coordinates: 426229..426696 (-)
• Length: 156 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N805_RS01685	421427..422332	-	906	WP_019470164.1	LysR family transcriptional regulator	-
N805_RS01690	422502..425432	-	2931	WP_019470165.1	aminotransferase	-
N805_RS01695	425657..426232	-	576	WP_019470166.1	PIN domain-containing protein	Toxin
N805_RS01700	426229..426696	-	468	WP_019470167.1	helix-turn-helix domain-containing protein	Antitoxin
N805_RS01705	426879..427142	-	264	WP_019470168.1	DUF3077 domain-containing protein	-
N805_RS01710	427298..427556	-	259	Protein_336	hypothetical protein	-
N805_RS01715	427977..429584	-	1608	WP_019470169.1	ABC transporter ATP-binding protein	-
N805_RS01720	429586..430605	-	1020	WP_016488246.1	ABC transporter permease	-
N805_RS01725	430607..431680	-	1074	WP_019470170.1	microcin C ABC transporter permease YejB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (9-115)

Antitoxin

• Helix-turn-helix domain, group 17 (84-132)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21671.86 Da
• Isoelectric Point: 4.8853

>T53137 WP_019470166.1 NZ_CP010979:c426232-425657 [Pseudomonas putida S13.1.2]
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSAGIHDEWKRNLLLNRPDLTPEHVDRTSSLMDAAVPDALVTDY
DSLVEGLDLPDEDDRHVLAAAIKCNASVIVTFNLKDFPKAVLGVFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRISLKN
PPHSVQQYLDRLLQQKLPETVKLLSEFKFLL

Nucleotide

• Length: 576 bp

>T53137 NZ_CP010979:c426232-425657 [Pseudomonas putida S13.1.2]
ATGAAGCACTCGCCCTTCACGGCCATATACGACGCGAACGTACTTTACCCTGCTCCCCTGCGTGATTTCCTGATGAACCT
GGCGCTGACGGGTATTTACCGGGCACGCTGGTCAGCGGGCATTCATGACGAGTGGAAGCGCAATCTGCTACTCAACCGAC
CTGACCTTACGCCTGAACATGTGGATCGCACGTCATCGCTAATGGATGCTGCGGTACCAGATGCACTCGTCACTGACTAC
GATTCACTGGTCGAAGGACTGGACTTGCCAGATGAGGATGATCGACATGTCCTGGCAGCGGCAATTAAGTGCAACGCTTC
GGTCATCGTCACCTTCAATTTGAAGGATTTTCCCAAGGCGGTTCTCGGGGTCTTCGATATTGAACCCTTGCATCCGGACG
ACTTCATCGCTGACCTGTGGGACCTGGACAAGGCAGCAGTCCTCGAAGCTGCCCAGCGCCAGCGAATATCGTTGAAGAAC
CCACCTCACAGCGTGCAGCAGTATCTCGACAGGCTGCTTCAGCAGAAGCTTCCCGAGACAGTGAAATTGCTTTCAGAATT
CAAGTTCCTCCTGTGA

Antitoxin

Protein

• Length: 156 a.a.
• Molecular weight: 17204.66 Da
• Isoelectric Point: 6.4943

>AT53137 WP_019470167.1 NZ_CP010979:c426696-426229 [Pseudomonas putida S13.1.2]
MTTANLSRNVLPDEKEIAVAVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPHLVKLLDEAVIPHTKTGRHRRVRFSDLVAYKDKRDGVSRAAMDALAAQAQELKMGYE

Nucleotide

• Length: 468 bp

>AT53137 NZ_CP010979:c426696-426229 [Pseudomonas putida S13.1.2]
ATGACCACCGCCAACCTCTCTCGCAATGTTCTTCCTGATGAAAAAGAAATTGCCGTGGCTGTCGAGTCAAGCCGCACGCT
AGCGGCGTTCCTCTCGACAAAATCAGATACCCAACGGATCGAACTGCTCAACGAGGAAAATCAGCGCCAGGTTGTTGAAG
TGCCTACCTTCGCCCTACGCCTGTTCGGCGAGATTCTCAGCGAGCTGGCGTTGGGGAACTCGGTCAAAGTCGTCCCAATC
CACGCCGAACTGACGACCCAGGAAGCAGCAGACCTGCTTAACGTCTCCCGGCCGCACTTGGTAAAGCTGCTCGACGAAGC
GGTGATTCCGCACACCAAGACGGGCCGCCATCGGCGTGTCAGATTCTCCGACCTGGTTGCCTACAAAGACAAACGTGACG
GGGTGAGCCGCGCTGCAATGGATGCGCTGGCAGCCCAAGCTCAGGAATTGAAGATGGGGTACGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A0C5RMW1