Detailed information of TA system TA053107

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 2097837..2098366
• Replicon: chromosome
• Accession: NZ_CP010945
• Organism: Pseudomonas fluorescens NCIMB 11764

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: B723_RS32060
• Protein ID: WP_080995108.1
• Coordinates: 2098100..2098366 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0K1QLI7
• Locus tag: B723_RS09470
• Protein ID: WP_017336496.1
• Coordinates: 2097837..2098100 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B723_RS09455	2093850..2096111	-	2262	WP_017336493.1	TonB-dependent siderophore receptor	-
B723_RS09460	2096318..2096998	+	681	WP_017336494.1	Fe2+-dependent dioxygenase	-
B723_RS09465	2096995..2097780	+	786	WP_017336495.1	sel1 repeat family protein	-
B723_RS09470	2097837..2098100	+	264	WP_017336496.1	ribbon-helix-helix domain-containing protein	Antitoxin
B723_RS32060	2098100..2098366	+	267	WP_080995108.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
B723_RS09475	2098458..2099621	-	1164	WP_008024420.1	type III PLP-dependent enzyme	-
B723_RS09480	2100115..2101272	-	1158	WP_017336497.1	ABC transporter ATP-binding protein	-
B723_RS09485	2101269..2101922	-	654	WP_007942812.1	ABC transporter permease	-
B723_RS09490	2101935..2102828	-	894	WP_017336498.1	glycine betaine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-86)

Antitoxin

• Ribbon-helix-helix protein, CopG (7-43)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10223.89 Da
• Isoelectric Point: 10.5293

>T53107 WP_080995108.1 NZ_CP010945:2098100-2098366 [Pseudomonas fluorescens NCIMB 11764]
MELKWTSKALSDLARLFDFLAVVNRPAAARTVQSLTQAPTALLSNPRIGERVDEFVPRDVRRLLVGHYEMRYEIQGSTLY
ILRLWHVR

Nucleotide

• Length: 267 bp

>T53107 NZ_CP010945:2098100-2098366 [Pseudomonas fluorescens NCIMB 11764]
ATGGAGTTGAAGTGGACGAGCAAGGCGTTATCGGACCTCGCCCGACTTTTTGATTTTCTTGCAGTGGTCAATCGTCCTGC
TGCAGCCCGCACCGTGCAATCTCTCACTCAGGCTCCTACAGCTTTACTCAGCAATCCGCGGATCGGAGAACGGGTTGACG
AGTTTGTACCGCGAGATGTGCGACGACTTTTGGTCGGCCATTACGAAATGCGGTATGAGATTCAAGGCTCAACGCTCTAC
ATCCTTCGTCTTTGGCATGTGAGATAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9738.07 Da
• Isoelectric Point: 5.0967

>AT53107 WP_017336496.1 NZ_CP010945:2097837-2098100 [Pseudomonas fluorescens NCIMB 11764]
MAATKVLTAHVPLELADKVDQMAAKMERSRGWIVKQALADWVDHEEARSRLTREAMADVDAGRVIDHQSVQAWAESLDTD
KPLPVPY

Nucleotide

• Length: 264 bp

>AT53107 NZ_CP010945:2097837-2098100 [Pseudomonas fluorescens NCIMB 11764]
ATGGCTGCTACCAAAGTGCTGACGGCCCATGTCCCCTTGGAACTGGCTGATAAAGTCGATCAGATGGCTGCGAAGATGGA
GCGTTCACGGGGCTGGATCGTGAAGCAAGCGCTTGCCGACTGGGTTGATCATGAAGAGGCGCGCAGCCGGCTTACTCGAG
AGGCAATGGCAGATGTTGACGCCGGACGAGTGATTGATCATCAGTCTGTCCAGGCCTGGGCAGAAAGTTTGGATACTGAT
AAGCCGCTGCCGGTCCCGTACTGA

Structures

Antitoxin

• AlphaFold DB: A0A0K1QLI7