Detailed information of TA system TA053075

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 1806428..1807944
• Replicon: chromosome
• Accession: NZ_CP010904
• Organism: Kiritimatiella glycovorans strain L21-Fru-AB

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: L21SP4_RS07460
• Protein ID: WP_052882068.1
• Coordinates: 1806428..1807348 (-)
• Length: 307 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: A0A0G3EEJ1
• Locus tag: L21SP4_RS07465
• Protein ID: WP_052882069.1
• Coordinates: 1807345..1807944 (-)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L21SP4_RS07445	1804949..1805467	+	519	WP_052882065.1	hypothetical protein	-
L21SP4_RS07450	1805528..1805974	-	447	WP_074041418.1	Rrf2 family transcriptional regulator	-
L21SP4_RS07455	1806009..1806431	-	423	WP_052882067.1	recombinase family protein	-
L21SP4_RS07460	1806428..1807348	-	921	WP_052882068.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
L21SP4_RS07465	1807345..1807944	-	600	WP_052882069.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
L21SP4_RS07470	1808419..1811055	-	2637	WP_144413793.1	hypothetical protein	-
L21SP4_RS07475	1811052..1812230	-	1179	WP_052882071.1	metallophosphoesterase	-
L21SP4_RS07480	1812245..1812460	-	216	WP_052882072.1	KTSC domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-277)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (11-53)

Sequences

Toxin

Protein

• Length: 307 a.a.
• Molecular weight: 34755.72 Da
• Isoelectric Point: 6.7668

>T53075 WP_052882068.1 NZ_CP010904:c1807348-1806428 [Kiritimatiella glycovorans]
VSTSRSHSIQARLLNYSREHQVNHNHTLTRYGIERLMYRLSRSSYADRFVLKGAMLFVLWLEDLHRPTQDLDLLGFGDLS
SSNLRNIFEDVCKLPVEDDGIEFSKDGIEIEEIREAEVYQGLRIKIPGRLGNTRLNVSVDVGFGDAVVPDPEKSDYPVLL
DLPRPEMKTYPRETVVAEKVDAMIVLGLLNSRMKDYYDLWTLAQRFPFDAALLAKAIDASLKRRGRELPSQTPPGLQDEF
VANPTKQTQWKGFLRRTIPDQADLELGEVVPAIREFLAPVLKSIVLGKALRLHWTPGSGWSANRSQ

Nucleotide

• Length: 921 bp

>T53075 NZ_CP010904:c1807348-1806428 [Kiritimatiella glycovorans]
GTGAGCACGTCCCGATCCCATTCGATTCAGGCCCGGCTGCTGAACTACTCGCGCGAGCATCAGGTGAACCACAACCACAC
GCTGACGCGCTATGGAATCGAACGCCTGATGTACCGCCTCTCCCGGTCGTCTTACGCGGACCGGTTCGTTCTGAAAGGAG
CGATGCTGTTCGTCCTCTGGCTGGAGGACTTGCATCGTCCGACGCAAGACCTGGATTTGCTCGGCTTCGGCGATCTCTCC
TCCTCCAACTTGAGAAACATTTTCGAGGATGTTTGCAAGTTGCCTGTCGAAGACGATGGGATCGAGTTCTCCAAGGACGG
AATCGAGATCGAGGAAATCAGGGAGGCGGAGGTCTATCAGGGGCTTCGGATCAAGATTCCGGGACGACTGGGAAACACCA
GGCTCAACGTCTCGGTCGATGTTGGATTCGGCGACGCCGTCGTTCCCGATCCGGAGAAGTCCGATTACCCCGTACTTCTC
GATCTTCCACGTCCCGAGATGAAGACATATCCCAGGGAAACGGTCGTGGCGGAGAAGGTCGACGCCATGATCGTGCTTGG
GCTCCTCAACAGTCGAATGAAGGACTACTACGATCTCTGGACGCTGGCCCAGCGATTTCCCTTCGATGCCGCTTTGCTCG
CCAAGGCGATTGATGCCTCTCTCAAACGGCGTGGCCGGGAACTGCCGTCGCAAACACCGCCCGGCCTTCAGGATGAATTT
GTGGCGAACCCAACCAAGCAGACACAGTGGAAGGGATTCCTGCGCCGTACGATTCCCGACCAGGCGGACCTTGAACTCGG
CGAGGTCGTTCCGGCGATTCGCGAGTTCCTCGCGCCGGTCCTGAAATCCATCGTCCTCGGCAAGGCGCTTCGCCTTCACT
GGACTCCAGGGAGCGGCTGGTCGGCAAACAGGTCGCAATGA

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22371.01 Da
• Isoelectric Point: 8.6252

>AT53075 WP_052882069.1 NZ_CP010904:c1807944-1807345 [Kiritimatiella glycovorans]
MTTHLENLMRVAETKGLIRARDLADHGIPRQYLSIACERGLLERRDRGLYALPGAIQTEHRSLVEVCTIVPHGVICLISA
LQFHGMTTQSPFEVWLAIGESKEIPRIGLVKLRIARFSAESLKAGVESHDVNGAELRVFSAAKTVADCFKYRNKIGVDVA
TEALRDYLRQRKGPIDDLTKYARVCRVERVMEPYLEALL

Nucleotide

• Length: 600 bp

>AT53075 NZ_CP010904:c1807944-1807345 [Kiritimatiella glycovorans]
ATGACGACGCACCTCGAAAACCTCATGCGCGTGGCCGAAACCAAAGGGCTGATCCGCGCCCGTGACCTCGCTGACCACGG
TATCCCGCGTCAGTATCTATCCATCGCTTGCGAGCGGGGGCTGCTGGAGCGACGGGATCGCGGCCTCTATGCGCTTCCCG
GCGCCATTCAGACGGAGCACCGCAGTTTGGTGGAGGTCTGCACGATCGTGCCCCATGGCGTGATCTGTCTGATTTCGGCG
CTTCAGTTTCACGGTATGACCACGCAAAGCCCTTTCGAGGTCTGGCTGGCCATTGGCGAGTCGAAGGAGATTCCCCGGAT
CGGCCTTGTCAAGCTTCGCATCGCGCGGTTCTCCGCAGAGTCGCTGAAGGCCGGCGTCGAATCGCACGATGTGAATGGCG
CAGAACTGCGGGTATTCTCCGCCGCGAAGACCGTCGCCGATTGCTTCAAGTACCGCAACAAGATCGGGGTGGACGTTGCC
ACCGAAGCGCTCCGGGATTACCTGCGCCAGCGCAAGGGGCCAATCGACGACCTGACGAAATACGCTCGAGTCTGCCGCGT
CGAGCGCGTCATGGAACCCTATCTGGAGGCGCTTCTGTGA

Structures

Antitoxin

• AlphaFold DB: A0A0G3EEJ1