Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1792966..1793525 Replicon chromosome
Accession NZ_CP010904
Organism Kiritimatiella glycovorans strain L21-Fru-AB

Toxin (Protein)


Gene name relE Uniprot ID A0A0G3EE76
Locus tag L21SP4_RS07405 Protein ID WP_052882058.1
Coordinates 1792966..1793280 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0G3EH66
Locus tag L21SP4_RS07410 Protein ID WP_052882059.1
Coordinates 1793268..1793525 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L21SP4_RS12405 1788203..1789078 + 876 Protein_1457 transposase -
L21SP4_RS07385 1789148..1789825 - 678 WP_052882054.1 DUF1614 domain-containing protein -
L21SP4_RS07390 1790022..1791686 + 1665 WP_052882055.1 hypothetical protein -
L21SP4_RS07395 1791839..1792183 - 345 WP_052882056.1 type II toxin-antitoxin system PemK/MazF family toxin -
L21SP4_RS07400 1792177..1792413 - 237 WP_052882057.1 hypothetical protein -
L21SP4_RS07405 1792966..1793280 - 315 WP_052882058.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L21SP4_RS07410 1793268..1793525 - 258 WP_052882059.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L21SP4_RS07415 1793692..1794750 + 1059 WP_052880849.1 IS30 family transposase -
L21SP4_RS07420 1794939..1796834 - 1896 WP_052882060.1 phosphoenolpyruvate carboxykinase (GTP) -
L21SP4_RS07425 1797062..1797973 + 912 WP_052882061.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12359.33 Da        Isoelectric Point: 7.8139

>T53074 WP_052882058.1 NZ_CP010904:c1793280-1792966 [Kiritimatiella glycovorans]
MARLIWTEPALLDLEEIAEYIALDDPLAASRYVQRVFDRVERLEAHQKSGKRPPELPRSPYREVVVPPCRVFYRIEGDAV
YILCVMRSERLLRTYLLDQRNREK

Download         Length: 315 bp

>T53074 NZ_CP010904:c1793280-1792966 [Kiritimatiella glycovorans]
ATGGCTCGGTTGATCTGGACCGAACCCGCGTTGCTGGATCTTGAGGAGATCGCCGAGTACATTGCGCTCGACGATCCTCT
TGCCGCATCCCGATACGTCCAGAGAGTATTTGATCGCGTCGAACGACTCGAAGCCCACCAGAAATCGGGGAAGCGACCAC
CTGAGCTGCCACGCTCGCCTTACCGGGAAGTCGTCGTCCCGCCGTGCCGCGTGTTCTACCGTATCGAGGGAGATGCCGTG
TACATTCTGTGCGTTATGCGATCAGAACGGTTGCTCCGGACGTACCTGCTCGATCAGAGAAACCGGGAGAAGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9875.44 Da        Isoelectric Point: 10.0415

>AT53074 WP_052882059.1 NZ_CP010904:c1793525-1793268 [Kiritimatiella glycovorans]
MKTELVTTLKRQATRVLSDLHDTGEPVLITEHGKPSAYLVDVDSYEFMQDRMRILEGIARGERAMLEKRTFSHAEARRKM
KKWLG

Download         Length: 258 bp

>AT53074 NZ_CP010904:c1793525-1793268 [Kiritimatiella glycovorans]
ATGAAAACAGAACTTGTCACAACGCTCAAGCGCCAAGCGACTCGCGTTTTGTCGGACCTCCATGACACGGGTGAACCGGT
GCTCATCACGGAACACGGGAAACCCTCGGCCTATCTGGTTGACGTGGATTCATACGAGTTCATGCAGGATCGGATGCGCA
TTCTTGAGGGCATCGCGCGCGGAGAGCGCGCGATGCTGGAAAAGCGCACCTTCTCGCATGCCGAGGCTAGACGAAAGATG
AAGAAATGGCTCGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0G3EE76

Antitoxin

Source ID Structure
AlphaFold DB A0A0G3EH66

References