Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1305724..1307593 Replicon chromosome
Accession NZ_CP010897
Organism Pandoraea vervacti strain NS15

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag UC34_RS05915 Protein ID WP_084070386.1
Coordinates 1305724..1306650 (+) Length 309 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag UC34_RS05920 Protein ID WP_174556781.1
Coordinates 1306718..1307593 (+) Length 292 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UC34_RS05890 1301032..1302108 + 1077 WP_044457804.1 porin -
UC34_RS05895 1302503..1303372 + 870 WP_150626100.1 ABC transporter ATP-binding protein -
UC34_RS05900 1303418..1304200 + 783 WP_044454623.1 ABC transporter permease -
UC34_RS05905 1304227..1305018 + 792 WP_084070385.1 SDR family oxidoreductase -
UC34_RS05910 1305070..1305627 + 558 WP_044454625.1 cupin domain-containing protein -
UC34_RS05915 1305724..1306650 + 927 WP_084070386.1 alpha/beta fold hydrolase Toxin
UC34_RS05920 1306718..1307593 + 876 WP_174556781.1 IclR family transcriptional regulator Antitoxin
UC34_RS05925 1307590..1308405 + 816 WP_044454627.1 SDR family oxidoreductase -
UC34_RS05930 1308398..1310050 + 1653 WP_044454629.1 thiamine pyrophosphate-binding protein -
UC34_RS05935 1310043..1310861 + 819 WP_044454631.1 aspartate dehydrogenase -
UC34_RS05940 1310875..1312371 + 1497 WP_044454633.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(59-293)

Antitoxin

Transcription regulator IclR, N-terminal

(27-75)


Sequences

Toxin        


Download         Length: 309 a.a.        Molecular weight: 32120.30 Da        Isoelectric Point: 4.9962

>T53068 WP_084070386.1 NZ_CP010897:1305724-1306650 [Pandoraea vervacti]
MSSQAIQSEVPVDDVVAPLRARLDAFPYRTVATRVGTVGYRCAGITSEAHDAHDAHVPVVMLHGIGSGAASWVAQLDASG
LDVALYAWDAPGYGETSNVAEAEPHAEAYADALEAWLDALGLDRVALVGHSLGAIMATKFASRAPQRVRGLFLCSPANGY
GKADPEARASKRDSRLAMLDKLGPDGMARERSDNLVAPDAADLPRAWVKWNMARVLPAGYRQATHLLSNGDVAGELAQYV
SALAGPVAVAVGAVDGITPPAACETIARVAGVPLQIIEGAGHASYIETPDMLNAALGAWLDRVAAGER

Download         Length: 927 bp

>T53068 NZ_CP010897:1305724-1306650 [Pandoraea vervacti]
ATGTCATCCCAAGCGATTCAGTCCGAAGTGCCAGTCGACGATGTCGTCGCGCCGCTGCGTGCGCGCCTCGACGCCTTCCC
GTACCGTACCGTCGCCACGCGCGTGGGCACGGTGGGCTATCGCTGCGCTGGAATCACGAGCGAGGCGCATGACGCGCATG
ACGCGCATGTCCCGGTCGTGATGCTGCATGGCATCGGCTCGGGCGCAGCGTCGTGGGTGGCACAGCTCGATGCCTCGGGC
CTTGACGTCGCCCTGTACGCATGGGATGCGCCCGGCTATGGCGAGACGTCCAACGTTGCCGAGGCCGAACCGCACGCGGA
GGCTTATGCCGATGCGCTCGAAGCCTGGCTCGACGCTCTGGGTCTGGATCGCGTTGCCCTGGTCGGTCATTCGCTTGGCG
CGATCATGGCGACGAAGTTTGCCAGCCGCGCGCCGCAACGCGTGCGCGGCCTTTTCCTGTGCTCGCCGGCCAATGGGTAT
GGCAAGGCCGACCCGGAAGCGCGCGCATCGAAGCGCGACAGCCGTCTGGCGATGCTCGACAAGCTCGGACCGGACGGCAT
GGCGCGCGAGCGCAGCGACAATCTGGTCGCGCCCGACGCTGCGGACCTGCCGCGTGCGTGGGTGAAATGGAACATGGCGC
GCGTGTTGCCCGCCGGTTACCGTCAGGCGACGCATCTGCTCTCGAACGGCGACGTTGCCGGTGAACTCGCGCAGTACGTG
AGCGCGCTCGCCGGTCCGGTCGCGGTGGCGGTGGGCGCCGTGGACGGCATCACGCCGCCGGCGGCATGCGAGACGATTGC
CCGAGTGGCGGGTGTGCCGCTGCAAATCATCGAAGGCGCGGGGCATGCGTCGTACATCGAAACGCCGGACATGCTCAATG
CTGCGCTTGGCGCGTGGCTCGACCGTGTCGCGGCAGGGGAGCGTTGA

Antitoxin


Download         Length: 292 a.a.        Molecular weight: 31741.19 Da        Isoelectric Point: 6.3575

>AT53068 WP_174556781.1 NZ_CP010897:1306718-1307593 [Pandoraea vervacti]
MSQDGQSEGDDVADSAPAESRYLVPGLERGLRILTQFSPREPVFSAPELSQRLGIPRTTVFRLLQTLEAMGFLERAGSEK
NFRLGVAVLRLGFEYLSSLELTDLGIPIIERLRDATQLTSHIVIRDGRDIVFVAKAQSVAGVFNSIKVNVGTRLPAHATV
HGHVLMGDLTLAELRALYPEKTLEKFTPQTPETLNELFERVREDAERGYAVSASSFERGISVVSAPVRNDAGRICAAITV
TIPRANIDASMLDAGLIGQVREAADALSHRLNYRPGADGQTTPYMKSLGLK

Download         Length: 876 bp

>AT53068 NZ_CP010897:1306718-1307593 [Pandoraea vervacti]
CTGTCCCAGGACGGGCAGAGCGAAGGCGACGACGTTGCCGATTCGGCGCCTGCCGAATCGCGCTACCTGGTGCCGGGGCT
CGAGCGCGGTCTGCGCATCCTGACGCAGTTCTCGCCGCGCGAGCCCGTGTTCAGCGCGCCGGAGTTGTCGCAGCGTCTGG
GCATTCCGCGCACGACCGTCTTTCGTCTGTTGCAGACGCTCGAAGCCATGGGTTTTCTGGAGCGTGCGGGCAGCGAGAAG
AATTTCCGTCTGGGCGTGGCCGTGCTGCGTCTGGGCTTCGAATACCTCAGTTCGCTGGAACTGACCGACCTGGGTATCCC
GATCATCGAGCGTCTGCGCGACGCCACGCAACTGACCTCGCACATCGTGATTCGCGACGGTCGCGACATCGTGTTCGTCG
CCAAGGCGCAGAGCGTTGCCGGCGTGTTCAACTCGATCAAGGTGAACGTCGGCACGCGCCTGCCGGCACACGCCACTGTG
CACGGCCACGTGCTCATGGGCGATTTGACGCTCGCGGAACTGCGGGCGCTGTACCCGGAGAAGACGCTGGAGAAATTCAC
GCCGCAAACGCCGGAAACGCTCAACGAATTGTTCGAACGCGTGCGCGAGGACGCCGAGCGTGGCTACGCCGTGTCGGCCT
CGTCGTTCGAGCGTGGCATCAGTGTCGTGAGCGCTCCGGTGCGCAACGACGCCGGGCGCATCTGCGCCGCGATCACGGTC
ACGATTCCGCGCGCGAACATCGATGCGTCGATGCTCGATGCGGGTCTGATCGGGCAAGTGCGCGAAGCGGCGGATGCGCT
CTCGCATCGCCTGAATTACCGGCCCGGCGCCGACGGCCAGACCACCCCCTACATGAAGTCACTGGGATTGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References