Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 2902905..2904187 | Replicon | chromosome |
| Accession | NZ_CP010892 | ||
| Organism | Pseudomonas sp. MRSN12121 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A0C5E409 |
| Locus tag | TO66_RS13320 | Protein ID | WP_044462754.1 |
| Coordinates | 2903603..2904187 (+) | Length | 195 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | TO66_RS13315 | Protein ID | WP_044462753.1 |
| Coordinates | 2902905..2903477 (+) | Length | 191 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| TO66_RS13300 | 2899476..2900666 | + | 1191 | WP_044462750.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| TO66_RS13305 | 2900659..2902074 | + | 1416 | WP_044462751.1 | aldehyde dehydrogenase family protein | - |
| TO66_RS13310 | 2902116..2902817 | + | 702 | WP_044462752.1 | NAD(P)H-dependent oxidoreductase | - |
| TO66_RS13315 | 2902905..2903477 | + | 573 | WP_044462753.1 | helix-turn-helix domain-containing protein | Antitoxin |
| TO66_RS13320 | 2903603..2904187 | + | 585 | WP_044462754.1 | HD domain-containing protein | Toxin |
| TO66_RS13325 | 2904232..2904744 | + | 513 | WP_044462755.1 | N-acetyltransferase | - |
| TO66_RS13330 | 2904920..2905909 | + | 990 | WP_044462756.1 | hypothetical protein | - |
| TO66_RS13335 | 2905906..2906946 | + | 1041 | WP_044462757.1 | membrane protein | - |
| TO66_RS13340 | 2906998..2907351 | - | 354 | WP_044462758.1 | hypothetical protein | - |
| TO66_RS13345 | 2907837..2908742 | + | 906 | WP_044462759.1 | NAD-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 195 a.a. Molecular weight: 21839.60 Da Isoelectric Point: 5.8869
>T53063 WP_044462754.1 NZ_CP010892:2903603-2904187 [Pseudomonas sp. MRSN12121]
MTDETLNGKLAFLREAERLKDVLRSAHTSGGRQESTAEHSWRLCLMVLVFEQELAGLDLLKLLKLCVIHDLGEAIHGDIP
AVSQAAHPHKSEQERADLLQLTRSLPPSLRASLLGLWEEYEAAATPEAQAVKALDKLETLLQHNQGRNPDDFDYGFNLGY
GRRYTSATPLFQALRERVDEDTRQRLRQQASNQA
MTDETLNGKLAFLREAERLKDVLRSAHTSGGRQESTAEHSWRLCLMVLVFEQELAGLDLLKLLKLCVIHDLGEAIHGDIP
AVSQAAHPHKSEQERADLLQLTRSLPPSLRASLLGLWEEYEAAATPEAQAVKALDKLETLLQHNQGRNPDDFDYGFNLGY
GRRYTSATPLFQALRERVDEDTRQRLRQQASNQA
Download Length: 585 bp
>T53063 NZ_CP010892:2903603-2904187 [Pseudomonas sp. MRSN12121]
ATGACTGACGAAACCCTCAACGGCAAACTGGCGTTCCTGCGCGAAGCGGAACGGCTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCGGCGGCCGCCAGGAAAGCACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGTGCTGGTTTTCGAGCAGGAAC
TGGCCGGCCTGGACCTGCTGAAACTGCTCAAGCTGTGTGTGATCCATGATCTGGGCGAGGCGATCCACGGCGATATCCCG
GCGGTGAGCCAGGCGGCCCATCCGCACAAGAGCGAGCAGGAACGCGCCGACCTGTTGCAGTTGACCCGTAGCCTGCCGCC
CTCGCTGCGCGCGAGCTTGCTCGGCTTGTGGGAAGAATATGAAGCCGCCGCTACGCCAGAGGCGCAGGCGGTCAAGGCGC
TGGACAAGCTGGAGACCCTGCTGCAACACAATCAGGGGCGCAACCCGGACGATTTCGACTACGGCTTCAACCTGGGTTAC
GGTCGCCGCTACACCAGCGCCACGCCGCTGTTCCAGGCGCTGCGCGAACGGGTCGACGAAGACACCCGGCAGCGCCTGCG
GCAGCAGGCATCGAACCAAGCCTGA
ATGACTGACGAAACCCTCAACGGCAAACTGGCGTTCCTGCGCGAAGCGGAACGGCTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCGGCGGCCGCCAGGAAAGCACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGTGCTGGTTTTCGAGCAGGAAC
TGGCCGGCCTGGACCTGCTGAAACTGCTCAAGCTGTGTGTGATCCATGATCTGGGCGAGGCGATCCACGGCGATATCCCG
GCGGTGAGCCAGGCGGCCCATCCGCACAAGAGCGAGCAGGAACGCGCCGACCTGTTGCAGTTGACCCGTAGCCTGCCGCC
CTCGCTGCGCGCGAGCTTGCTCGGCTTGTGGGAAGAATATGAAGCCGCCGCTACGCCAGAGGCGCAGGCGGTCAAGGCGC
TGGACAAGCTGGAGACCCTGCTGCAACACAATCAGGGGCGCAACCCGGACGATTTCGACTACGGCTTCAACCTGGGTTAC
GGTCGCCGCTACACCAGCGCCACGCCGCTGTTCCAGGCGCTGCGCGAACGGGTCGACGAAGACACCCGGCAGCGCCTGCG
GCAGCAGGCATCGAACCAAGCCTGA
Antitoxin
Download Length: 191 a.a. Molecular weight: 20974.20 Da Isoelectric Point: 7.7426
>AT53063 WP_044462753.1 NZ_CP010892:2902905-2903477 [Pseudomonas sp. MRSN12121]
MAASFPPSPLLSTTHLGVALRRWRLLHRVKQEHAAQLFKVAQSTISRWENGVQAMEPPEQARLEQLLAARLHAAADQALA
RLVNDNPRPVHLVCDLTHRLLACSPARAAQFSVPLGELLGESLWRFCTAEIVRQEAALDDLGWRSLLAPPSLEFVSGAND
CAIVPIHQSLCRWTRLTLSDGTAARLVETL
MAASFPPSPLLSTTHLGVALRRWRLLHRVKQEHAAQLFKVAQSTISRWENGVQAMEPPEQARLEQLLAARLHAAADQALA
RLVNDNPRPVHLVCDLTHRLLACSPARAAQFSVPLGELLGESLWRFCTAEIVRQEAALDDLGWRSLLAPPSLEFVSGAND
CAIVPIHQSLCRWTRLTLSDGTAARLVETL
Download Length: 573 bp
>AT53063 NZ_CP010892:2902905-2903477 [Pseudomonas sp. MRSN12121]
ATGGCTGCCTCTTTCCCGCCGTCGCCGTTGCTGTCGACCACTCACCTGGGCGTCGCGCTCAGGCGCTGGCGCCTGTTGCA
CCGGGTCAAGCAGGAGCATGCGGCGCAGTTGTTCAAGGTCGCCCAGTCGACCATTTCCCGTTGGGAAAACGGCGTGCAGG
CCATGGAGCCGCCGGAGCAGGCGCGGCTCGAACAATTACTGGCGGCCCGCCTGCACGCGGCGGCCGACCAGGCCCTGGCG
CGGCTGGTCAACGACAACCCGCGGCCCGTGCATTTGGTGTGCGACCTGACCCACCGCCTGCTGGCTTGTTCGCCGGCGCG
GGCGGCGCAGTTCTCGGTGCCGCTCGGCGAGCTGCTGGGCGAATCGCTGTGGCGCTTTTGCACGGCCGAGATCGTCCGCC
AGGAGGCGGCGCTGGACGATCTGGGCTGGCGCAGCCTGCTGGCGCCGCCTTCCCTGGAGTTCGTCAGCGGGGCCAACGAT
TGCGCCATCGTGCCGATCCATCAGAGCCTCTGCCGCTGGACCCGCCTGACCCTGTCCGACGGCACGGCGGCGCGCCTGGT
GGAAACCCTCTGA
ATGGCTGCCTCTTTCCCGCCGTCGCCGTTGCTGTCGACCACTCACCTGGGCGTCGCGCTCAGGCGCTGGCGCCTGTTGCA
CCGGGTCAAGCAGGAGCATGCGGCGCAGTTGTTCAAGGTCGCCCAGTCGACCATTTCCCGTTGGGAAAACGGCGTGCAGG
CCATGGAGCCGCCGGAGCAGGCGCGGCTCGAACAATTACTGGCGGCCCGCCTGCACGCGGCGGCCGACCAGGCCCTGGCG
CGGCTGGTCAACGACAACCCGCGGCCCGTGCATTTGGTGTGCGACCTGACCCACCGCCTGCTGGCTTGTTCGCCGGCGCG
GGCGGCGCAGTTCTCGGTGCCGCTCGGCGAGCTGCTGGGCGAATCGCTGTGGCGCTTTTGCACGGCCGAGATCGTCCGCC
AGGAGGCGGCGCTGGACGATCTGGGCTGGCGCAGCCTGCTGGCGCCGCCTTCCCTGGAGTTCGTCAGCGGGGCCAACGAT
TGCGCCATCGTGCCGATCCATCAGAGCCTCTGCCGCTGGACCCGCCTGACCCTGTCCGACGGCACGGCGGCGCGCCTGGT
GGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|