Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 995752..996290 Replicon chromosome
Accession NZ_CP010892
Organism Pseudomonas sp. MRSN12121

Toxin (Protein)


Gene name relE Uniprot ID A0A0C5EEU9
Locus tag TO66_RS04430 Protein ID WP_044461181.1
Coordinates 996012..996290 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0C5DZ09
Locus tag TO66_RS04425 Protein ID WP_044461180.1
Coordinates 995752..996015 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TO66_RS04410 991741..994020 - 2280 WP_044461177.1 TonB-dependent siderophore receptor -
TO66_RS04415 994226..994906 + 681 WP_044461178.1 Fe2+-dependent dioxygenase -
TO66_RS04420 994910..995695 + 786 WP_044461179.1 sel1 repeat family protein -
TO66_RS04425 995752..996015 + 264 WP_044461180.1 ribbon-helix-helix domain-containing protein Antitoxin
TO66_RS04430 996012..996290 + 279 WP_044461181.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TO66_RS04435 996365..997528 - 1164 WP_044461182.1 type III PLP-dependent enzyme -
TO66_RS04440 998106..999263 - 1158 WP_044461183.1 ABC transporter ATP-binding protein -
TO66_RS04445 999260..999913 - 654 WP_044461184.1 ABC transporter permease -
TO66_RS04450 999927..1000829 - 903 WP_044461185.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10781.50 Da        Isoelectric Point: 10.5216

>T53058 WP_044461181.1 NZ_CP010892:996012-996290 [Pseudomonas sp. MRSN12121]
VRALKWTSKALSDLARLFEFLAPVNRSAAARTVQSLTRAPETLLANPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQGMTL
YILRVWHVREDR

Download         Length: 279 bp

>T53058 NZ_CP010892:996012-996290 [Pseudomonas sp. MRSN12121]
GTGAGGGCGTTGAAGTGGACGAGCAAGGCGCTATCGGACCTGGCTCGGCTGTTTGAGTTTCTGGCTCCCGTGAATCGCTC
GGCCGCTGCCCGAACGGTGCAATCCCTGACACGAGCCCCGGAGACCCTGCTGGCCAATCCGCGTATCGGCGAGCAGTTGG
AGGAGTTTCAACCTCGCGATGTCCGGCGTTTGTTGGTAGGGCCCTACGAGATGCGTTATGAGATTCAGGGGATGACGCTC
TATATCCTGCGGGTGTGGCACGTGCGGGAAGACCGATAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9727.02 Da        Isoelectric Point: 4.6112

>AT53058 WP_044461180.1 NZ_CP010892:995752-996015 [Pseudomonas sp. MRSN12121]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDAGQVIDHQAVQAWAESLMND
DPLPVPK

Download         Length: 264 bp

>AT53058 NZ_CP010892:995752-996015 [Pseudomonas sp. MRSN12121]
ATGACTGCCACTAAAGTGCTGACGGCCCATGTGCCCTTGGAGTTGGCCGACAAGGTCGACCAGATGGCCTCCCGGCTGGA
GCGTTCGCGCGGCTGGATCGTCAAGCAGGCGCTGGTGGCCTGGGTCGACCAGGAAGAGGAGCGCAGCCGCCTGACGCACG
AGGCCCTGGCCGATGTGGACGCGGGGCAGGTCATCGACCATCAGGCCGTTCAGGCATGGGCCGAGAGCCTGATGAATGAT
GATCCTTTACCGGTGCCCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5EEU9

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5DZ09

References