Detailed information of TA system TA053056

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 184785..185301
• Replicon: chromosome
• Accession: NZ_CP010892
• Organism: Pseudomonas sp. MRSN12121

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: A0A285EY61
• Locus tag: TO66_RS00800
• Protein ID: WP_009041601.1
• Coordinates: 185020..185301 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: TO66_RS32145
• Protein ID: WP_082061026.1
• Coordinates: 184785..185030 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
TO66_RS00770	180032..181654	+	1623	WP_044460521.1	glycosyltransferase family 39 protein	-
TO66_RS00775	181620..182378	-	759	WP_044460522.1	slipin family protein	-
TO66_RS00780	182380..183765	-	1386	WP_044460523.1	nodulation protein NfeD	-
TO66_RS00785	183973..184434	+	462	WP_044460524.1	YbaK/EbsC family protein	-
TO66_RS00790	184475..184720	+	246	WP_044460525.1	DUF2789 domain-containing protein	-
TO66_RS32145	184785..185030	+	246	WP_082061026.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
TO66_RS00800	185020..185301	+	282	WP_009041601.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
TO66_RS00805	185428..185856	+	429	WP_044460527.1	winged helix DNA-binding protein	-
TO66_RS00810	185853..187937	+	2085	WP_044460528.1	FUSC family protein	-
TO66_RS00815	187934..188143	+	210	WP_044460529.1	DUF1656 domain-containing protein	-
TO66_RS00820	188140..189036	+	897	WP_044460530.1	HlyD family secretion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-70)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10879.81 Da
• Isoelectric Point: 10.5797

>T53056 WP_009041601.1 NZ_CP010892:185020-185301 [Pseudomonas sp. MRSN12121]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Nucleotide

• Length: 282 bp

>T53056 NZ_CP010892:185020-185301 [Pseudomonas sp. MRSN12121]
ATGACTTATAAGCTCCAGTTCCTGCCTTCGGCCCGCAAGGAATGGGACAAGCTCGGGCATACCCTGCGCGAGCAATTCAA
GAAGAAGCTGGCCGAGCGACTGGAAATGCCCCGGGTGCCAGCAGATGCCCTGCACGGCATGGCGGACTGCTACAAGATCA
AACTCAAGGCCTCGGGTTATCGCCTGGTCTACCAGGTGATCGAGGATCAGGTCGTGGTCTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGTGCCGTGTATGAGCGGGCACGAAAGCGTTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8818.16 Da
• Isoelectric Point: 5.0216

>AT53056 WP_082061026.1 NZ_CP010892:184785-185030 [Pseudomonas sp. MRSN12121]
MQSVLADKAVSVSELKKNPSAVLNGAHGGPVAVLNHNRVMGYMVPADVFEALMERLDDLELAEIVRARRHETPIPVSLDD
L

Nucleotide

• Length: 246 bp

>AT53056 NZ_CP010892:184785-185030 [Pseudomonas sp. MRSN12121]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAATCCCTCGGCCGTCCTGAATGGCGCGCA
CGGTGGCCCGGTTGCAGTGCTCAATCACAATCGGGTCATGGGGTATATGGTTCCGGCCGATGTGTTCGAAGCCTTGATGG
AACGTCTTGATGACCTGGAGCTGGCGGAGATTGTGCGCGCGCGTCGTCATGAGACGCCGATCCCGGTAAGCCTGGATGAC
TTATAA

Structures

Toxin

• AlphaFold DB: A0A285EY61