Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/ParE-CC2985 |
Location | 2219173..2219701 | Replicon | chromosome |
Accession | NZ_CP010836 | ||
Organism | Sphingomonas hengshuiensis strain WHSC-8 isolate soil of Hengshui Lake |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A7U4LFC8 |
Locus tag | TS85_RS09810 | Protein ID | WP_044331903.1 |
Coordinates | 2219411..2219701 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A7U5HVR8 |
Locus tag | TS85_RS09805 | Protein ID | WP_044336122.1 |
Coordinates | 2219173..2219418 (+) | Length | 82 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
TS85_RS09785 | 2215113..2215466 | + | 354 | WP_044331899.1 | hypothetical protein | - |
TS85_RS24610 | 2215630..2216631 | + | 1002 | WP_077228505.1 | IS30 family transposase | - |
TS85_RS09795 | 2216784..2218187 | + | 1404 | WP_044331901.1 | serine hydrolase | - |
TS85_RS09800 | 2218184..2219098 | + | 915 | WP_044331902.1 | hypothetical protein | - |
TS85_RS09805 | 2219173..2219418 | + | 246 | WP_044336122.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
TS85_RS09810 | 2219411..2219701 | + | 291 | WP_044331903.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
TS85_RS09815 | 2219720..2222104 | - | 2385 | WP_044336123.1 | membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family | - |
TS85_RS09820 | 2222485..2223879 | + | 1395 | WP_044331904.1 | leucyl aminopeptidase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11257.92 Da Isoelectric Point: 9.0791
>T52955 WP_044331903.1 NZ_CP010836:2219411-2219701 [Sphingomonas hengshuiensis]
MAEYRLSPKAQRDLESVFDYTRAQWGLPQAMRYIDLIEAACADLAEAPHRAQDCTHIRPGYRRRTVEQHVLYFRLASHGI
AIIRILHQRMDTARHL
MAEYRLSPKAQRDLESVFDYTRAQWGLPQAMRYIDLIEAACADLAEAPHRAQDCTHIRPGYRRRTVEQHVLYFRLASHGI
AIIRILHQRMDTARHL
Download Length: 291 bp
>T52955 NZ_CP010836:2219411-2219701 [Sphingomonas hengshuiensis]
ATGGCTGAATATCGGCTCAGTCCGAAGGCACAGCGCGATCTCGAATCGGTATTCGATTATACCAGGGCGCAATGGGGATT
GCCCCAGGCCATGCGCTACATCGATCTGATTGAAGCCGCCTGCGCCGATCTTGCCGAAGCGCCGCATCGCGCGCAGGACT
GCACGCACATCCGCCCTGGCTATCGCCGGCGGACTGTAGAGCAGCACGTCCTCTATTTTCGGCTGGCGAGCCATGGCATC
GCCATCATTCGAATCCTCCATCAGCGCATGGATACGGCCCGTCACCTGTGA
ATGGCTGAATATCGGCTCAGTCCGAAGGCACAGCGCGATCTCGAATCGGTATTCGATTATACCAGGGCGCAATGGGGATT
GCCCCAGGCCATGCGCTACATCGATCTGATTGAAGCCGCCTGCGCCGATCTTGCCGAAGCGCCGCATCGCGCGCAGGACT
GCACGCACATCCGCCCTGGCTATCGCCGGCGGACTGTAGAGCAGCACGTCCTCTATTTTCGGCTGGCGAGCCATGGCATC
GCCATCATTCGAATCCTCCATCAGCGCATGGATACGGCCCGTCACCTGTGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 9278.26 Da Isoelectric Point: 5.7135
>AT52955 WP_044336122.1 NZ_CP010836:2219173-2219418 [Sphingomonas hengshuiensis]
MATVRKTITLTEQQDAWIAAQIDAGHYTNDSEAIRDLIRREQERSFEIESLRHALIAGEQSGEPERFDFAAFKRRKSAQN
G
MATVRKTITLTEQQDAWIAAQIDAGHYTNDSEAIRDLIRREQERSFEIESLRHALIAGEQSGEPERFDFAAFKRRKSAQN
G
Download Length: 246 bp
>AT52955 NZ_CP010836:2219173-2219418 [Sphingomonas hengshuiensis]
ATGGCGACGGTACGCAAGACGATCACGCTGACCGAGCAGCAGGATGCGTGGATCGCCGCGCAGATCGACGCCGGCCACTA
TACCAACGACAGCGAGGCGATCCGCGACCTTATCCGGCGCGAGCAGGAGCGGAGTTTCGAGATTGAGAGCCTGCGCCATG
CGTTGATCGCGGGCGAGCAGAGCGGCGAGCCCGAGCGCTTCGACTTCGCGGCGTTCAAGCGGCGAAAATCCGCGCAAAAT
GGCTGA
ATGGCGACGGTACGCAAGACGATCACGCTGACCGAGCAGCAGGATGCGTGGATCGCCGCGCAGATCGACGCCGGCCACTA
TACCAACGACAGCGAGGCGATCCGCGACCTTATCCGGCGCGAGCAGGAGCGGAGTTTCGAGATTGAGAGCCTGCGCCATG
CGTTGATCGCGGGCGAGCAGAGCGGCGAGCCCGAGCGCTTCGACTTCGCGGCGTTCAAGCGGCGAAAATCCGCGCAAAAT
GGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U4LFC8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U5HVR8 |