Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1387057..1387291 Replicon chromosome
Accession NZ_CP010829
Organism Shigella sonnei strain FORC_011

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1387187..1387290 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1387057..1387291 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC11_RS07165 1383612..1384274 - 663 WP_000944256.1 exodeoxyribonuclease X -
FORC11_RS07170 1384298..1384954 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
FORC11_RS07175 1385056..1385286 - 231 WP_000916763.1 DNA polymerase III subunit theta -
FORC11_RS07180 1385425..1385799 + 375 WP_000168735.1 CopC domain-containing protein YobA -
FORC11_RS07185 1385803..1386675 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
FORC11_RS07190 1386688..1387029 + 342 WP_000976476.1 YebY family protein -
- 1387057..1387291 - 235 - - Antitoxin
- 1387187..1387290 + 104 - - Toxin
FORC11_RS07200 1387422..1388498 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
FORC11_RS07205 1388535..1388780 - 246 Protein_1355 IS1 family transposase -
FORC11_RS31130 1390114..1390568 - 455 Protein_1357 IS1-like element IS1A family transposase -
FORC11_RS27935 1390597..1390857 - 261 WP_077447296.1 excisionase -
FORC11_RS07230 1391002..1392158 + 1157 WP_087879964.1 IS3-like element IS600 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 / ipaH9.8 1329122..1414252 85130


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52931 NZ_CP010829:1387187-1387290 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT52931 NZ_CP010829:c1387291-1387057 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References