Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1837956..1838227 Replicon chromosome
Accession NZ_CP010816
Organism Escherichia coli strain BL21 (TaKaRa)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1837994..1838097 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1837956..1838227 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SR36_RS09290 (SR36_09290) 1835113..1836552 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SR36_RS09295 (SR36_09295) 1836670..1836906 + 237 WP_001295499.1 DUF1480 family protein -
SR36_RS09300 (SR36_09300) 1837011..1837202 + 192 WP_001296140.1 YebW family protein -
SR36_RS09305 (SR36_09305) 1837203..1837859 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1837956..1838227 + 272 - - Antitoxin
- 1837994..1838097 - 104 - - Toxin
SR36_RS09315 (SR36_09315) 1838254..1838595 - 342 WP_000976472.1 YebY family protein -
SR36_RS09320 (SR36_09320) 1838608..1839480 - 873 WP_000879293.1 copper homeostasis membrane protein CopD -
SR36_RS09325 (SR36_09325) 1839484..1839858 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SR36_RS09330 (SR36_09330) 1839997..1840227 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SR36_RS09335 (SR36_09335) 1840329..1840985 + 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
SR36_RS09340 (SR36_09340) 1841009..1841671 + 663 WP_000944245.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52908 NZ_CP010816:c1838097-1837994 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT52908 NZ_CP010816:1837956-1838227 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References