Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1150634..1151111 Replicon chromosome
Accession NZ_CP010802
Organism Desulfuromonas soudanensis strain WTL

Toxin (Protein)


Gene name - Uniprot ID A0A0M4D549
Locus tag DSOUD_RS05090 Protein ID WP_053549987.1
Coordinates 1150851..1151111 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A0M4D060
Locus tag DSOUD_RS05085 Protein ID WP_053549986.1
Coordinates 1150634..1150861 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSOUD_RS05065 1146232..1146855 - 624 Protein_1020 hypothetical protein -
DSOUD_RS05070 1146995..1148194 + 1200 WP_053549983.1 class I SAM-dependent rRNA methyltransferase -
DSOUD_RS05075 1148184..1149884 - 1701 WP_053549984.1 alkaline phosphatase family protein -
DSOUD_RS05080 1150047..1150559 - 513 WP_053549985.1 peptidyl-prolyl cis-trans isomerase -
DSOUD_RS05085 1150634..1150861 - 228 WP_053549986.1 hypothetical protein Antitoxin
DSOUD_RS05090 1150851..1151111 - 261 WP_053549987.1 BrnT family toxin Toxin
DSOUD_RS05095 1151192..1151578 - 387 WP_053549988.1 hypothetical protein -
DSOUD_RS05100 1151633..1152274 - 642 WP_053549989.1 hypothetical protein -
DSOUD_RS05105 1152271..1153335 - 1065 WP_053549990.1 virulence RhuM family protein -
DSOUD_RS05110 1153351..1153746 - 396 WP_053549991.1 type II toxin-antitoxin system VapC family toxin -
DSOUD_RS05115 1153733..1153972 - 240 WP_053549992.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
DSOUD_RS05120 1154251..1154850 - 600 WP_053549993.1 transglutaminase-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9993.22 Da        Isoelectric Point: 4.8616

>T52868 WP_053549987.1 NZ_CP010802:c1151111-1150851 [Desulfuromonas soudanensis]
MSFEYDPQKSAANFEKHGIDFDEAQMLWGDSDLLEVPAKTGDEPRWLVVGKIDGKHWSAVITYRHEVIRLISVRRSRQEE
IALYES

Download         Length: 261 bp

>T52868 NZ_CP010802:c1151111-1150851 [Desulfuromonas soudanensis]
ATGAGCTTCGAATACGACCCACAAAAGAGTGCCGCCAATTTTGAAAAGCACGGCATCGATTTTGATGAAGCGCAAATGCT
CTGGGGCGATTCCGACCTGCTGGAAGTGCCGGCGAAAACCGGCGATGAACCGAGATGGCTTGTCGTCGGGAAGATTGATG
GCAAACATTGGTCGGCGGTGATCACTTATCGCCACGAAGTCATTCGCCTCATCTCGGTCCGGCGCTCGCGACAAGAGGAG
ATCGCACTGTATGAAAGCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8827.11 Da        Isoelectric Point: 7.0162

>AT52868 WP_053549986.1 NZ_CP010802:c1150861-1150634 [Desulfuromonas soudanensis]
MKAEDFDKKFDQGESVIDDLDLSKARRPEQEQRRVNVDFPVWMIHSLDKEARRLGVPRQSIIKMWLAEKLEKTAG

Download         Length: 228 bp

>AT52868 NZ_CP010802:c1150861-1150634 [Desulfuromonas soudanensis]
ATGAAAGCTGAAGATTTCGACAAAAAATTTGATCAAGGCGAAAGCGTCATTGACGATCTTGACCTGTCCAAGGCACGCCG
TCCCGAACAGGAACAGCGCAGAGTCAATGTCGATTTTCCGGTCTGGATGATTCATTCTCTGGACAAGGAGGCGCGTCGAC
TCGGGGTGCCCCGCCAGTCGATTATCAAGATGTGGCTTGCCGAAAAGCTCGAAAAAACAGCTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0M4D549

Antitoxin

Source ID Structure
AlphaFold DB A0A0M4D060

References