Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2684881..2685542 Replicon chromosome
Accession NZ_CP010554
Organism Rugosibacter aromaticivorans strain Ca6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PG1C_RS13285 Protein ID WP_202635212.1
Coordinates 2684881..2685294 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PG1C_RS13290 Protein ID WP_202635213.1
Coordinates 2685291..2685542 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG1C_RS13270 2682110..2683336 + 1227 WP_202635209.1 porin -
PG1C_RS13275 2683405..2683995 - 591 WP_202635210.1 esterase -
PG1C_RS13280 2684017..2684844 - 828 WP_202635211.1 undecaprenyl-diphosphate phosphatase -
PG1C_RS13285 2684881..2685294 - 414 WP_202635212.1 type II toxin-antitoxin system VapC family toxin Toxin
PG1C_RS13290 2685291..2685542 - 252 WP_202635213.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PG1C_RS13295 2685952..2687820 - 1869 WP_202635214.1 phosphomethylpyrimidine synthase ThiC -
PG1C_RS13300 2688273..2688938 + 666 WP_202637076.1 TetR/AcrR family transcriptional regulator -
PG1C_RS13305 2689014..2690063 + 1050 WP_202635215.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-62)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15157.46 Da        Isoelectric Point: 6.4735

>T52803 WP_202635212.1 NZ_CP010554:c2685294-2684881 [Rugosibacter aromaticivorans]
MSYLLDTNVLSELRRKTPNAGVVEWFARRPASTLFLSVLTLGELRKGVEGMADADRRTALLDWLEAELPIFFTGRILSVD
VQVADRWGRLMAAAKRPVPAIDSLLAATAAHHGLSLVTRNVRDFVDSGLDVINPWTD

Download         Length: 414 bp

>T52803 NZ_CP010554:c2685294-2684881 [Rugosibacter aromaticivorans]
TTGAGCTATCTGCTCGATACCAATGTTCTCTCGGAACTGCGCCGCAAAACGCCCAACGCTGGTGTTGTCGAGTGGTTTGC
CCGGCGTCCGGCATCCACCTTGTTCCTGAGTGTGTTGACGCTGGGCGAATTGCGCAAGGGTGTCGAAGGCATGGCTGACG
CAGATCGCCGGACCGCCCTGCTGGATTGGCTCGAAGCGGAACTGCCGATCTTCTTTACCGGCCGGATTCTCTCAGTCGAT
GTGCAGGTGGCTGACCGCTGGGGGCGGTTGATGGCGGCAGCGAAGCGCCCGGTTCCGGCTATCGACAGCCTATTGGCAGC
GACCGCCGCGCATCATGGCCTGAGCCTGGTCACTCGCAACGTGCGCGATTTTGTTGATTCAGGATTGGATGTCATCAACC
CGTGGACCGATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9356.58 Da        Isoelectric Point: 5.1114

>AT52803 WP_202635213.1 NZ_CP010554:c2685542-2685291 [Rugosibacter aromaticivorans]
MHTWQMQEAKARLSEVVKLAESEGPQDITLHGRSVAVVLSRATFEHLSGSGQSLVEFMRQSPLYGLEEIEFERDRSAARE
VVL

Download         Length: 252 bp

>AT52803 NZ_CP010554:c2685542-2685291 [Rugosibacter aromaticivorans]
ATGCACACATGGCAAATGCAAGAAGCGAAAGCGCGCCTGTCTGAAGTCGTAAAACTCGCTGAAAGCGAGGGGCCGCAAGA
CATCACGCTGCACGGCCGGTCAGTGGCTGTGGTGCTGTCACGGGCAACCTTTGAGCACCTCTCAGGCAGCGGACAATCAC
TCGTGGAGTTCATGCGCCAATCGCCGTTGTATGGGCTCGAAGAAATCGAGTTCGAACGCGACCGCAGCGCCGCGCGTGAG
GTCGTGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References