Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 2335681..2336183 Replicon chromosome
Accession NZ_CP010554
Organism Rugosibacter aromaticivorans strain Ca6

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PG1C_RS11625 Protein ID WP_202634923.1
Coordinates 2335681..2335935 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag PG1C_RS11630 Protein ID WP_202634924.1
Coordinates 2335932..2336183 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG1C_RS11585 2331613..2331957 - 345 WP_202634916.1 hypothetical protein -
PG1C_RS11590 2332048..2332461 + 414 WP_202634917.1 hypothetical protein -
PG1C_RS11595 2332484..2333143 + 660 WP_202634918.1 hypothetical protein -
PG1C_RS11600 2333342..2333623 + 282 WP_202634919.1 type II toxin-antitoxin system RelE/ParE family toxin -
PG1C_RS11605 2333637..2333963 + 327 WP_202634920.1 HigA family addiction module antidote protein -
PG1C_RS11610 2334072..2334305 + 234 WP_202634921.1 hypothetical protein -
PG1C_RS11615 2334287..2334484 + 198 WP_202637050.1 type II toxin-antitoxin system HicA family toxin -
PG1C_RS11620 2334803..2335486 + 684 WP_202634922.1 type 1 glutamine amidotransferase domain-containing protein -
PG1C_RS11625 2335681..2335935 - 255 WP_202634923.1 Txe/YoeB family addiction module toxin Toxin
PG1C_RS11630 2335932..2336183 - 252 WP_202634924.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PG1C_RS11635 2336539..2336796 + 258 WP_202634925.1 BrnT family toxin -
PG1C_RS11640 2336800..2337075 + 276 WP_202634926.1 hypothetical protein -
PG1C_RS11645 2337206..2337505 + 300 WP_202634927.1 GIY-YIG nuclease family protein -
PG1C_RS11650 2338096..2340488 + 2393 Protein_2289 5-histidylcysteine sulfoxide synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10323.90 Da        Isoelectric Point: 9.8319

>T52802 WP_202634923.1 NZ_CP010554:c2335935-2335681 [Rugosibacter aromaticivorans]
MKLVFADEAWEDYLYWQKRDKRMVERINKLIRETQREPFTGVGKPEPLKHALSGFWSRRITDEHRMVYRVEDNALLIAQL
RFHY

Download         Length: 255 bp

>T52802 NZ_CP010554:c2335935-2335681 [Rugosibacter aromaticivorans]
ATGAAGCTGGTCTTTGCAGATGAGGCATGGGAAGACTACCTCTATTGGCAAAAGCGAGACAAACGTATGGTTGAACGGAT
TAACAAGTTGATACGCGAGACGCAACGCGAGCCCTTCACCGGAGTTGGAAAGCCTGAACCTTTAAAGCACGCGCTATCAG
GGTTCTGGTCACGTCGCATAACAGACGAGCATCGCATGGTATATCGCGTCGAAGACAATGCACTGTTGATTGCCCAATTG
CGCTTTCATTACTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9075.54 Da        Isoelectric Point: 8.9767

>AT52802 WP_202634924.1 NZ_CP010554:c2336183-2335932 [Rugosibacter aromaticivorans]
MDAITYTTIRANLASAMDRVCNDHEALIITRNGEQAVVMLSLEDYKALEETAYLLRTPANAKRLLTAVGQLNAGKGVARK
LVK

Download         Length: 252 bp

>AT52802 NZ_CP010554:c2336183-2335932 [Rugosibacter aromaticivorans]
ATGGATGCAATTACCTACACTACTATCCGCGCAAACCTCGCTAGCGCTATGGATCGGGTTTGCAACGATCACGAAGCTTT
AATTATCACCCGCAACGGAGAACAGGCGGTGGTGATGCTCTCGCTCGAAGACTACAAGGCGCTTGAAGAAACCGCCTACC
TCTTGCGCACACCCGCCAACGCCAAGCGCCTCTTGACGGCGGTCGGACAACTAAACGCCGGCAAAGGCGTTGCGCGGAAA
TTGGTTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References