Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1816571..1817193 Replicon chromosome
Accession NZ_CP010554
Organism Rugosibacter aromaticivorans strain Ca6

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag PG1C_RS09080 Protein ID WP_202637001.1
Coordinates 1816571..1816873 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag PG1C_RS09085 Protein ID WP_202634486.1
Coordinates 1816870..1817193 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG1C_RS09050 1812296..1813459 - 1164 WP_202634480.1 ATP-binding protein -
PG1C_RS09055 1813669..1813947 + 279 WP_202634481.1 DUF1778 domain-containing protein -
PG1C_RS09060 1813944..1814450 + 507 WP_202634482.1 GNAT family N-acetyltransferase -
PG1C_RS09065 1814487..1815620 - 1134 WP_202634483.1 ATP-binding protein -
PG1C_RS09070 1815926..1816207 + 282 WP_202634484.1 helix-turn-helix domain-containing protein -
PG1C_RS09075 1816265..1816435 + 171 WP_202634485.1 hypothetical protein -
PG1C_RS09080 1816571..1816873 + 303 WP_202637001.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG1C_RS09085 1816870..1817193 + 324 WP_202634486.1 helix-turn-helix domain-containing protein Antitoxin
PG1C_RS09090 1817434..1817685 - 252 WP_202634487.1 hypothetical protein -
PG1C_RS09095 1817877..1819325 - 1449 WP_202634488.1 hypothetical protein -
PG1C_RS09100 1819380..1820225 - 846 WP_202634489.1 sulfotransferase -
PG1C_RS09105 1820530..1821468 - 939 WP_202634490.1 glycosyltransferase family 2 protein -
PG1C_RS09110 1821476..1821874 - 399 WP_202634491.1 GtrA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-89)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-89)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10944.51 Da        Isoelectric Point: 9.8119

>T52799 WP_202637001.1 NZ_CP010554:1816571-1816873 [Rugosibacter aromaticivorans]
MPAEVQSTFGYALHQAQIGKKHEQTKPLKGFGSAGILEVVEDSGGGTFRAVYTVKFSDAVYVLHCFQKKSTHGIATPKPD
MDVIRERLKAAEAHSKGERK

Download         Length: 303 bp

>T52799 NZ_CP010554:1816571-1816873 [Rugosibacter aromaticivorans]
ATGCCCGCCGAGGTGCAATCCACCTTCGGCTATGCACTGCATCAAGCGCAGATCGGGAAGAAGCACGAACAGACGAAACC
GCTCAAGGGCTTCGGATCAGCGGGCATTCTTGAAGTAGTTGAAGACTCTGGTGGTGGCACGTTTCGCGCCGTCTACACAG
TCAAATTCAGCGACGCGGTTTATGTCCTGCATTGCTTTCAGAAGAAATCGACGCATGGGATTGCAACTCCCAAGCCGGAC
ATGGATGTAATTCGGGAACGATTGAAGGCGGCGGAAGCGCACTCCAAAGGAGAACGGAAATGA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11553.55 Da        Isoelectric Point: 10.2057

>AT52799 WP_202634486.1 NZ_CP010554:1816870-1817193 [Rugosibacter aromaticivorans]
MIEIEESSGNVYADLGMADADEMIVKAQLATKIGEIIKGRKWSQQQAADVLGIPQPKLSKMLRGQFRGISEAKMLDCLVR
LGRNVQIVVGPARRAASSGRVAVVFAV

Download         Length: 324 bp

>AT52799 NZ_CP010554:1816870-1817193 [Rugosibacter aromaticivorans]
ATGATTGAAATCGAAGAAAGCAGCGGCAACGTCTACGCCGATCTAGGCATGGCCGACGCCGACGAAATGATCGTCAAAGC
ACAGCTTGCAACCAAAATTGGCGAAATCATCAAAGGCAGGAAGTGGAGCCAGCAGCAAGCCGCCGATGTTCTAGGCATTC
CACAGCCGAAGCTATCCAAAATGCTGCGCGGTCAGTTTCGCGGTATCAGTGAAGCGAAGATGCTTGATTGTCTGGTGCGG
CTTGGTCGAAACGTGCAAATCGTCGTCGGCCCGGCTCGCCGTGCGGCTTCGTCCGGTCGCGTTGCTGTAGTGTTTGCCGT
GTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References