Detailed information of TA system TA052799

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 1816571..1817193
• Replicon: chromosome
• Accession: NZ_CP010554
• Organism: Rugosibacter aromaticivorans strain Ca6

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: PG1C_RS09080
• Protein ID: WP_202637001.1
• Coordinates: 1816571..1816873 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: PG1C_RS09085
• Protein ID: WP_202634486.1
• Coordinates: 1816870..1817193 (+)
• Length: 108 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PG1C_RS09050	1812296..1813459	-	1164	WP_202634480.1	ATP-binding protein	-
PG1C_RS09055	1813669..1813947	+	279	WP_202634481.1	DUF1778 domain-containing protein	-
PG1C_RS09060	1813944..1814450	+	507	WP_202634482.1	GNAT family N-acetyltransferase	-
PG1C_RS09065	1814487..1815620	-	1134	WP_202634483.1	ATP-binding protein	-
PG1C_RS09070	1815926..1816207	+	282	WP_202634484.1	helix-turn-helix domain-containing protein	-
PG1C_RS09075	1816265..1816435	+	171	WP_202634485.1	hypothetical protein	-
PG1C_RS09080	1816571..1816873	+	303	WP_202637001.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PG1C_RS09085	1816870..1817193	+	324	WP_202634486.1	helix-turn-helix domain-containing protein	Antitoxin
PG1C_RS09090	1817434..1817685	-	252	WP_202634487.1	hypothetical protein	-
PG1C_RS09095	1817877..1819325	-	1449	WP_202634488.1	hypothetical protein	-
PG1C_RS09100	1819380..1820225	-	846	WP_202634489.1	sulfotransferase	-
PG1C_RS09105	1820530..1821468	-	939	WP_202634490.1	glycosyltransferase family 2 protein	-
PG1C_RS09110	1821476..1821874	-	399	WP_202634491.1	GtrA family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (1-89)

Antitoxin

• HigA2-like, helix-turn-helix domain (11-89)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 10944.51 Da
• Isoelectric Point: 9.8119

>T52799 WP_202637001.1 NZ_CP010554:1816571-1816873 [Rugosibacter aromaticivorans]
MPAEVQSTFGYALHQAQIGKKHEQTKPLKGFGSAGILEVVEDSGGGTFRAVYTVKFSDAVYVLHCFQKKSTHGIATPKPD
MDVIRERLKAAEAHSKGERK

Nucleotide

• Length: 303 bp

>T52799 NZ_CP010554:1816571-1816873 [Rugosibacter aromaticivorans]
ATGCCCGCCGAGGTGCAATCCACCTTCGGCTATGCACTGCATCAAGCGCAGATCGGGAAGAAGCACGAACAGACGAAACC
GCTCAAGGGCTTCGGATCAGCGGGCATTCTTGAAGTAGTTGAAGACTCTGGTGGTGGCACGTTTCGCGCCGTCTACACAG
TCAAATTCAGCGACGCGGTTTATGTCCTGCATTGCTTTCAGAAGAAATCGACGCATGGGATTGCAACTCCCAAGCCGGAC
ATGGATGTAATTCGGGAACGATTGAAGGCGGCGGAAGCGCACTCCAAAGGAGAACGGAAATGA

Antitoxin

Protein

• Length: 108 a.a.
• Molecular weight: 11553.55 Da
• Isoelectric Point: 10.2057

>AT52799 WP_202634486.1 NZ_CP010554:1816870-1817193 [Rugosibacter aromaticivorans]
MIEIEESSGNVYADLGMADADEMIVKAQLATKIGEIIKGRKWSQQQAADVLGIPQPKLSKMLRGQFRGISEAKMLDCLVR
LGRNVQIVVGPARRAASSGRVAVVFAV

Nucleotide

• Length: 324 bp

>AT52799 NZ_CP010554:1816870-1817193 [Rugosibacter aromaticivorans]
ATGATTGAAATCGAAGAAAGCAGCGGCAACGTCTACGCCGATCTAGGCATGGCCGACGCCGACGAAATGATCGTCAAAGC
ACAGCTTGCAACCAAAATTGGCGAAATCATCAAAGGCAGGAAGTGGAGCCAGCAGCAAGCCGCCGATGTTCTAGGCATTC
CACAGCCGAAGCTATCCAAAATGCTGCGCGGTCAGTTTCGCGGTATCAGTGAAGCGAAGATGCTTGATTGTCTGGTGCGG
CTTGGTCGAAACGTGCAAATCGTCGTCGGCCCGGCTCGCCGTGCGGCTTCGTCCGGTCGCGTTGCTGTAGTGTTTGCCGT
GTGA