Detailed information of TA system TA052798

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 1813669..1814450
• Replicon: chromosome
• Accession: NZ_CP010554
• Organism: Rugosibacter aromaticivorans strain Ca6

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: PG1C_RS09060
• Protein ID: WP_202634482.1
• Coordinates: 1813944..1814450 (+)
• Length: 169 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: -
• Locus tag: PG1C_RS09055
• Protein ID: WP_202634481.1
• Coordinates: 1813669..1813947 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PG1C_RS09030	1809210..1810097	-	888	WP_202634476.1	NAD-dependent epimerase/dehydratase family protein	-
PG1C_RS09035	1810100..1810996	-	897	WP_202634477.1	glycosyltransferase family 2 protein	-
PG1C_RS09040	1811248..1811556	-	309	WP_202634478.1	type II toxin-antitoxin system RelE/ParE family toxin	-
PG1C_RS09045	1811553..1811804	-	252	WP_202634479.1	type II toxin-antitoxin system ParD family antitoxin	-
PG1C_RS09050	1812296..1813459	-	1164	WP_202634480.1	ATP-binding protein	-
PG1C_RS09055	1813669..1813947	+	279	WP_202634481.1	DUF1778 domain-containing protein	Antitoxin
PG1C_RS09060	1813944..1814450	+	507	WP_202634482.1	GNAT family N-acetyltransferase	Toxin
PG1C_RS09065	1814487..1815620	-	1134	WP_202634483.1	ATP-binding protein	-
PG1C_RS09070	1815926..1816207	+	282	WP_202634484.1	helix-turn-helix domain-containing protein	-
PG1C_RS09075	1816265..1816435	+	171	WP_202634485.1	hypothetical protein	-
PG1C_RS09080	1816571..1816873	+	303	WP_202637001.1	type II toxin-antitoxin system RelE/ParE family toxin	-
PG1C_RS09085	1816870..1817193	+	324	WP_202634486.1	helix-turn-helix domain-containing protein	-
PG1C_RS09090	1817434..1817685	-	252	WP_202634487.1	hypothetical protein	-
PG1C_RS09095	1817877..1819325	-	1449	WP_202634488.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (43-146)

Antitoxin

• Vibrio phage ICP1, Orf50 (11-85)

Sequences

Toxin

Protein

• Length: 169 a.a.
• Molecular weight: 18300.09 Da
• Isoelectric Point: 7.7458

>T52798 WP_202634482.1 NZ_CP010554:1813944-1814450 [Rugosibacter aromaticivorans]
MSTAYEPIRKLSVADHVEQFDCGQPGLNQFLQRYAFVNQKANSAQTYVCCDGGGVVGFYSLVVGSVDLEDAPVRVAKSLA
RHPVPVMILARLAVDRDHQGKGLGKALLKDALLRTVQAADIAGVRCLLVHAKDDAARQSYASWEFTPSPTDPYHLFLMLK
DLKALLTG

Nucleotide

• Length: 507 bp

>T52798 NZ_CP010554:1813944-1814450 [Rugosibacter aromaticivorans]
TTGAGCACAGCGTATGAGCCGATCCGCAAACTCTCGGTTGCGGATCACGTCGAGCAGTTTGACTGTGGGCAACCGGGACT
GAACCAGTTCCTGCAGCGTTACGCCTTCGTCAACCAGAAAGCCAACAGTGCGCAAACTTACGTCTGCTGCGATGGCGGTG
GCGTGGTGGGGTTCTACAGTCTGGTGGTTGGCAGCGTCGATCTGGAAGATGCGCCGGTACGGGTCGCGAAGAGCTTGGCC
CGTCATCCGGTGCCTGTGATGATTCTGGCTCGACTCGCTGTTGATCGTGATCACCAGGGTAAAGGACTTGGCAAGGCATT
GCTCAAAGACGCATTGCTGCGTACAGTGCAAGCCGCCGATATCGCAGGCGTACGTTGCTTGCTGGTCCATGCCAAGGATG
ATGCTGCGCGGCAATCGTACGCGTCTTGGGAGTTCACGCCAAGTCCGACCGATCCCTACCACTTGTTCTTGATGCTCAAA
GACCTCAAGGCATTGTTAACCGGTTAA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10132.51 Da
• Isoelectric Point: 10.1007

>AT52798 WP_202634481.1 NZ_CP010554:1813669-1813947 [Rugosibacter aromaticivorans]
MSTLNSSKSERIDVRASSSVKQLLQEAARACHKNVSEFLLDAGVTAANQALADRRQFVLNDDQWQAFQEALNRPVQAKPR
LKKLLGEPGVLG

Nucleotide

• Length: 279 bp

>AT52798 NZ_CP010554:1813669-1813947 [Rugosibacter aromaticivorans]
ATGAGCACCTTGAACTCATCAAAAAGCGAACGGATTGATGTCCGTGCCAGCAGCTCTGTCAAGCAACTGCTGCAAGAAGC
TGCGCGTGCCTGCCACAAGAATGTCAGCGAGTTTTTGCTTGACGCGGGCGTGACAGCAGCCAACCAAGCGCTCGCTGACC
GTCGCCAGTTTGTACTCAACGACGATCAGTGGCAAGCGTTTCAGGAGGCGCTGAACCGCCCTGTTCAGGCTAAGCCCCGC
CTGAAGAAGCTGCTCGGTGAACCTGGTGTGCTTGGTTGA