Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1972626..1972770 Replicon chromosome
Accession NZ_CP010523
Organism Klebsiella variicola strain DSM 15968

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1972662..1972764 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1972626..1972770 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SP68_RS09225 1967756..1969816 + 2061 WP_012541258.1 oligopeptidase B -
SP68_RS09230 1969820..1970479 - 660 WP_022066251.1 exodeoxyribonuclease X -
SP68_RS09235 1970558..1970788 - 231 WP_012541260.1 DNA polymerase III subunit theta -
SP68_RS09240 1970902..1971276 + 375 WP_008804269.1 CopC domain-containing protein YobA -
SP68_RS09245 1971280..1972149 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
SP68_RS09250 1972166..1972504 + 339 WP_008804271.1 YebY family protein -
- 1972626..1972770 - 145 - - Antitoxin
- 1972662..1972764 + 103 - - Toxin
SP68_RS27785 1973149..1973292 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
SP68_RS09255 1973396..1974385 - 990 WP_032691211.1 VirK/YbjX family protein -
SP68_RS09260 1974521..1975174 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
SP68_RS09265 1975171..1975362 - 192 WP_002911395.1 YebW family protein -
SP68_RS09270 1975460..1975699 - 240 WP_002911393.1 YebV family protein -
SP68_RS09275 1975815..1977248 - 1434 WP_012967754.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T52750 NZ_CP010523:1972662-1972764 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT52750 NZ_CP010523:c1972770-1972626 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References