Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-AbrB
Location 997932..998578 Replicon chromosome
Accession NZ_CP010515
Organism Acidilobus sp. 7A

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SE86_RS04985 Protein ID WP_117354539.1
Coordinates 998189..998578 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SE86_RS04980 Protein ID WP_117354538.1
Coordinates 997932..998192 (+) Length 87 a.a.

Genomic Context

SE86_RS04960SE86_RS04975SE86_RS04980SE86_RS04985SE86_RS05005SE86_RS08250SE86_RS04965SE86_RS04970SE86_RS04990SE86_RS04995SE86_RS05000SE86_RS05010
Location: 993474..993896 (423 bp)
Type: Others
Protein ID: WP_117354535.1
Location: 997281..997706 (426 bp)
Type: Others
Protein ID: WP_211096498.1
Location: 997932..998192 (261 bp)
Type: Antitoxin
Protein ID: WP_117354538.1
Location: 998189..998578 (390 bp)
Type: Toxin
Protein ID: WP_117354539.1
Location: 1001578..1002810 (1233 bp)
Type: Others
Protein ID: WP_211096501.1
Location: 993003..993299 (297 bp)
Type: Others
Protein ID: WP_117354534.1
Location: 993899..995062 (1164 bp)
Type: Others
Protein ID: WP_148666783.1
Location: 995076..996797 (1722 bp)
Type: Others
Protein ID: WP_117354537.1
Location: 998747..999718 (972 bp)
Type: Others
Protein ID: WP_211096499.1
Location: 999781..1001244 (1464 bp)
Type: Others
Protein ID: WP_211096500.1
Location: 1001244..1001456 (213 bp)
Type: Others
Protein ID: WP_117354540.1
Location: 1002807..1003316 (510 bp)
Type: Others
Protein ID: WP_117354542.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SE86_RS08250993003..993299-297WP_117354534.1FAD-dependent oxidoreductase-
SE86_RS04960 (SE86_04890)993474..993896+423WP_117354535.1SCP2 sterol-binding domain-containing protein-
SE86_RS04965 (SE86_04895)993899..995062-1164WP_148666783.1iron-containing alcohol dehydrogenase-
SE86_RS04970 (SE86_04900)995076..996797-1722WP_117354537.1thiamine pyrophosphate-binding protein-
SE86_RS04975 (SE86_04905)997281..997706+426WP_211096498.1hypothetical protein-
SE86_RS04980 (SE86_04910)997932..998192+261WP_117354538.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
SE86_RS04985 (SE86_04915)998189..998578+390WP_117354539.1type II toxin-antitoxin system VapC family toxinToxin
SE86_RS04990 (SE86_04920)998747..999718-972WP_211096499.1dihydropteroate synthase-
SE86_RS04995 (SE86_04925)999781..1001244-1464WP_211096500.1hypothetical protein-
SE86_RS05000 (SE86_04930)1001244..1001456-213WP_117354540.1DUF3311 domain-containing protein-
SE86_RS05005 (SE86_04935)1001578..1002810+1233WP_211096501.1M20 family metallopeptidase-
SE86_RS050101002807..1003316-510WP_117354542.1ParB N-terminal domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

SpoVT-AbrB domain

(4-46)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14891.25 Da        Isoelectric Point: 4.6286

>T52738 WP_117354539.1 NZ_CP010515:998189-998578 [Acidilobus sp. 7A]
VIFVDANFLIYLNLGVKEIEGYYLKLLSEESLATNPLVLDEVIYVSKKKYGVRLEDTLDFLDNVVLPNSVVLPLTINEYR
RAREVMLKYSLNPSDALHVAVMLNNSIRRILSEDTDFDRVKEVERVWLG

Download         Length: 390 bp

>T52738 NZ_CP010515:998189-998578 [Acidilobus sp. 7A]
GTGATATTCGTGGACGCTAACTTCCTAATTTATCTCAACCTCGGCGTGAAGGAGATCGAGGGCTATTACCTGAAGCTCCT
GTCAGAGGAGTCCCTCGCCACCAACCCGCTTGTCCTGGACGAGGTAATTTATGTCTCTAAGAAAAAGTACGGCGTTAGGC
TTGAGGACACCTTAGACTTCCTAGATAACGTTGTGCTGCCAAACTCTGTAGTCCTTCCACTAACGATTAATGAGTACAGG
AGGGCCAGGGAGGTCATGTTAAAGTACTCGCTAAACCCCTCCGACGCGCTCCACGTGGCTGTGATGCTGAACAACTCCAT
AAGGAGGATCCTGAGCGAGGACACGGACTTCGACAGGGTTAAGGAGGTTGAGAGGGTCTGGCTGGGCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9799.36 Da        Isoelectric Point: 7.0198

>AT52738 WP_117354538.1 NZ_CP010515:997932-998192 [Acidilobus sp. 7A]
MTAKVEVGRKGYIIIPKSIRELIGIKEGDVLTLTVENGRIVLEPERRVSLPEVARRLREHEEKVRKYAKEARLGDLAGVS
LEDEFE

Download         Length: 261 bp

>AT52738 NZ_CP010515:997932-998192 [Acidilobus sp. 7A]
TTGACTGCAAAGGTAGAGGTCGGGAGGAAGGGCTACATAATAATTCCTAAGAGCATAAGGGAGCTGATTGGGATAAAGGA
GGGGGACGTGCTGACCTTGACCGTTGAGAATGGAAGGATAGTGCTGGAGCCGGAGAGGAGGGTCAGCCTGCCTGAGGTGG
CTAGGAGGCTCAGGGAGCACGAGGAGAAAGTGAGAAAGTACGCTAAGGAGGCCAGGCTGGGCGACCTCGCTGGCGTGAGC
CTAGAGGATGAGTTCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References