Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2719434..2719705 Replicon chromosome
Accession NZ_CP010445
Organism Escherichia coli K-12 strain K-12 MG1655

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2719472..2719575 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2719434..2719705 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SF31_RS13530 2716591..2718030 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
SF31_RS13535 2718148..2718384 + 237 WP_001295499.1 DUF1480 family protein -
SF31_RS13540 2718489..2718680 + 192 WP_000457842.1 YebW family protein -
SF31_RS13545 2718681..2719337 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2719434..2719705 + 272 - - Antitoxin
- 2719472..2719575 - 104 - - Toxin
SF31_RS13555 2719733..2720074 - 342 WP_000976476.1 YebY family protein -
SF31_RS13560 2720087..2720959 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
SF31_RS13565 2720963..2721337 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SF31_RS13570 2721476..2721706 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SF31_RS13575 2721808..2722464 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
SF31_RS13580 2722488..2723150 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T52715 NZ_CP010445:c2719575-2719472 [Escherichia coli K-12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT52715 NZ_CP010445:2719434-2719705 [Escherichia coli K-12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References